Results 41 to 50 of about 97,184 (241)
ABSTRACT Background The robotic‐assisted extended “Sistrunk” approach (RESA) is a minimally invasive technique providing access to hypopharyngeal and laryngeal structures via a submental incision and vallecular pharyngotomy, bypassing the base of tongue.
Bartosz Wojtera +5 more
wiley +1 more source
ABSTRACT Background Following promising initial results of the robotic‐assisted extended “Sistrunk” approach (RESA) that uses a submental incision to hypopharyngeal and laryngeal tumors, bypassing the base of tongue, we report its further development: submental approach robotic‐assisted neck dissection (SARAND), intended to enable bilateral neck ...
Bartosz P. Wojtera +5 more
wiley +1 more source
Exercise intolerance and systemic manifestations of pulmonary emphysema in a mouse model
Background Systemic effects of chronic obstructive pulmonary disease (COPD) significantly contribute to severity and mortality of the disease. We aimed to develop a COPD/emphysema model exhibiting systemic manifestations of the disease.
Hasenfuss Gerd +6 more
doaj +1 more source
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni +26 more
wiley +1 more source
Hypervision Proton Surgery: The Future Direction of Proton Therapy
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley +1 more source
Background Chronic obstructive pulmonary disease (COPD) has been a major public health problem. Although pulmonary function test remains the primary diagnostic method, quantitative computed tomography (QCT) analysis has become more significant in the ...
Taghreed Abdelaziz Nasr +4 more
doaj +1 more source
Changes of CEA Diagnostic Performance Under the New Reference Interval Stratified by Age and Sex
Our study included patients with lung cancer, breast cancer, and colorectal cancer and apparently healthy individuals, conducted a large case–control study to assess the effects of age and sex on serum concentrations and positive rates of CEA, established age‐ and sex‐stratified reference intervals using indirect methods.
Ke Zhang, Xiarui Ye
wiley +1 more source
Background Emphysema influences the appearance of lung tissue in computed tomography (CT). We evaluated whether this affects lung nodule detection by artificial intelligence (AI) and human readers (HR).
Nikos Sourlos +10 more
doaj +1 more source
Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley +1 more source

