Results 11 to 20 of about 122,393 (245)

Smoking history and emphysema in asthma–COPD overlap

International Journal of COPD, 2017
Kazuyoshi Kurashima,1 Yotaro Takaku,1 Chie Ohta,1 Noboru Takayanagi,1 Tsutomu Yanagisawa,1 Tetsu Kanauchi,2 Osamu Takahashi3 1Department of Respiratory Medicine, 2Department of Radiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, 3Center ...
Kurashima K, Takaku Y, Ohta C, Takayanagi N, Yanagisawa T, Kanauchi T, Takahashi O   +6 more
doaj   +1 more source

Comparison of efficacy of long-acting bronchodilators in emphysema dominant and emphysema nondominant chronic obstructive pulmonary disease

International Journal of COPD, 2011
Keisaku Fujimoto1, Yoshiaki Kitaguchi2, Shintaro Kanda2, Kazuhisa Urushihata2, Masayuki Hanaoka2, Keishi Kubo21Department of Biomedical Laboratory Sciences, 2First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano,
Fujimoto K, Kitaguchi Y, Kanda S, Urushihata K, Hanaoka M, Kubo K   +5 more
doaj   +1 more source

Emphysema in an 11-month-old boy with alpha-1 antitrypsin deficiency. [PDF]

Pediatr Investig
Pediatric development of emphysema in Alpha‐1 Antitrypsin Deficiency (A1ATD) has been rarely described. In this case report, we document an 11‐month boy with A1ATD phenotype PiZZ with basilar centrilobular emphysema, the earliest such documented case.
Yi I, Williams R, Chandrasekar L, Al-Qatarneh S.   +3 more
europepmc   +2 more sources

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Traumatic Orbital Emphysema Following Blunt Trauma and Nose Blowing [PDF]

, 2023
Orbital emphysema commonly resolves with no morbidity. However, sight-threatening complications, such as central retinal artery occlusion and ischemic optic neuropathy, may occur, which can result in poor visual outcomes.
Chong, Jia Cherng, Lim, Xiao Chien, Lim, Lik Thai, Hanida, Hanafi, Ng, Qi Xiong   +4 more
core   +1 more source

Diagnosing and mapping pulmonary emphysema on X-ray projection images [PDF]

, 2013
To assess whether grating-based X-ray dark-field imaging can increase the sensitivity of X-ray projection images in the diagnosis of pulmonary emphysema and allow for a more accurate assessment of emphysema distribution.
Pfeiffer, Franz, Meinel, Felix G., Schleede, Simone, Herzen, Julia, Ruth, Ronald, Nikolaou, Konstantin, Bohla, Alexander, Bech, Martin, Yildirim, Ali Ö., Reiser, Maximilian F., Auweter, Sigrid, Bamberg, Fabian, Schwab, Felix, Loewen, Rod, Gifford, Martin, Achterhold, Klaus, Eickelberg, Oliver   +16 more
core   +1 more source

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]

, 2011
Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Wu, Shaoping, Jae-Woong Hwang, Sundar, Isaac K, Sun, Jun, Isaac K. Sundar, Hwang, Jae-woong, Rahman, Irfan, Shaoping Wu, Irfan Rahman, Jun Sun   +9 more
core   +1 more source

Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep [PDF]

, 2006
Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large-animal model of emphysema using repeated LPS administration into sheep lung segments.
Blundell, Richard, Rhind, Susan; id_orcid, McLean, Nicola, Rhind, Susan, Milne, Elspeth, Woodall, Chris, Collie, D David S, Baker, Alison, Sallenave, Jean-Michel   +8 more
core   +1 more source

Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L

Signal Transduction and Targeted Therapy, 2023
Patients with chronic obstructive pulmonary disease (COPD) who exhibit elevated blood eosinophil levels often experience worsened lung function and more severe emphysema.
Xia Xu, Tao Yu, Lingling Dong, Rainer Glauben, Siyuan Wu, Ronghua Huang, Shiwei Qumu, Chenli Chang, Jing Guo, Lin Pan, Ting Yang, Xin Lin, Ke Huang, Zhihua Chen, Chen Wang   +14 more
doaj   +1 more source

Comparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysema [PDF]

, 2015
Background Emphysema is the main pathological feature of COPD and also is the focus of the related research. Although several emphysema animal models have been established, exact comparison of findings is seldom.
Hong-Liang Zhang, Zhi-Hui He, Ji-Ru Ye, Yan Chen, Jun Cao, Sheng-Dong He, Ping Chen   +6 more
core   +1 more source