Results 61 to 70 of about 218,651 (379)

New Spirometry Indices for Detecting Mild Airflow Obstruction. [PDF]

, 2018
The diagnosis of chronic obstructive pulmonary disease (COPD) relies on demonstration of airflow obstruction. Traditional spirometric indices miss a number of subjects with respiratory symptoms or structural lung disease on imaging.
Barjaktarevic, Igor, Bhakta, Nirav R, Bhatt, Surya P, Bodduluri, Sandeep, Castaldi, Peter J, Cooper, Christopher B, Dransfield, Mark T, Eberlein, Michael, Han, MeiLan K, Kim, Young-Il, Nakhmani, Arie, Sciurba, Frank C, Wilson, Carla G, Woodruff, Prescott G   +13 more
core   +2 more sources

Endobronchial Valves for Emphysema without Interlobar Collateral Ventilation.

New England Journal of Medicine, 2015
BACKGROUND Bronchoscopic lung-volume reduction with the use of one-way endobronchial valves is a potential treatment for patients with severe emphysema.
K. Klooster, N. T. ten Hacken, J. Hartman, H. Kerstjens, E. V. van Rikxoort, D. Slebos   +5 more
semanticscholar   +1 more source

Gas Bubbles from Biodegradable Magnesium Implants Convey Mechanical Cues and Promote Immune Cell Stimulation

Advanced Science, EarlyView.
Bubbles in soft tissue are the unavoidable consequence of magnesium implant degradation in patients, yet their biological significance remains unclear. Using advanced imaging and spatial transcriptomics, this study reveals a pronounced inflammatory and mechanical response near bubbles, contrasting with pro‐regenerative events closer to the implant ...
Heithem Ben Amara, Jincy Philip, Omar Omar, Peter Thomsen   +3 more
wiley   +1 more source

Value of metalloproteinases in predicting COPD in heavy urban smokers

Respiratory Research, 2020
Background Emphysema in asymptomatic heavy smokers can be detected during CT-scan screening for lung cancer. Metalloproteinases (MMPs) have been found to play a role in the pathogenesis of chronic obstructive pulmonary disease and to possibly serve as ...
Jun-Chieh J. Tsay, Yingjie Hu, Judith D. Goldberg, Bin Wang, Soumya Vijayalekshmy, Ting-An Yie, Katrina Bantis, Daniel H. Sterman, William N. Rom   +8 more
doaj   +1 more source

Empyema necessitans and a persistent air leak associated with rupture of an anaerobic lung abscess due to bacteroides [PDF]

, 2017
No abstract ...
Blyth, Kevin G., Sharma, Varun
core   +1 more source

Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) is a significant cause of morbidity and mortality among patients with RA, yet effective risk stratification for RA‐ILD is lacking. We sought to characterize unique peripheral blood biomarker signatures in RA that could improve RA‐ILD discrimination beyond clinical and genetic ...
Austin M. Wheeler, Joshua F. Baker, Thomas R. Riley IV, Tate M. Johnson, Yangyuna Yang, Punyasha Roul, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Gail Kerr, Dana P. Ascherman, Paul Monach, Andreas Reimold, Scott Matson, Jill A. Poole, Michael J. Duryee, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +18 more
wiley   +1 more source

A study of subcutaneous emphysema, factors contributing to its development, resolution and management with different modalities

Monaldi Archives for Chest Disease, 2023
Subcutaneous emphysema is defined as an escape of air in subcutaneous tissue. It is one of the most common complications after inter-costal chest tube drainage.
Mukesh Goyal, Jose K. Jimmy, Ramakant Dixit, Deepak Kumar Garg   +3 more
doaj   +1 more source

Alveolar macrophages and the diagnosis of drowning [PDF]

, 1993
In the present study, we examined the number of alveolar macrophages in lung tissue from 17 cases of fresh water drowning, 22 cases of acute death and 6 cases of lung emphysema.
A. Nerlich, Brinkmann, Brinkmann, Cordell, Janssen, Mueller, P. Betz, Püschel, R. Penning, Reh, Reh, Timperman, W. Eisenmenger   +12 more
core   +1 more source

Autocrine insulin-like growth factor 2 signaling as a potential target in the associated development of pulmonary emphysema and cancer in smokers

Inflammation and Regeneration
Background Tobacco smoking causes pulmonary inflammation, resulting in emphysema, an independent risk factor for lung cancer. Induction of insulin-like growth factor 2 (IGF2) in response to lung injury by tobacco carcinogens, 4-(methylnitrosamino)-1-(3 ...
Hye-Jin Boo, Hye-Young Min, Heung-Bin Lim, Euni Lee, Ho-Young Lee   +4 more
doaj   +1 more source

Relationship between diffusion capacity and small airway abnormality in COPDGene. [PDF]

, 2019
Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but the relationship between SAD and DLCO is undescribed. We hypothesized that in mild COPD,
Casaburi, Richard, Criner, Rachel N, Curtis, Jeffrey L, Galbán, Craig J, Han, Mei Lan K, Hatt, Charles R, Kazerooni, Ella A, Labaki, Wassim W, Lynch, David A, MacIntyre, Neil R, Make, Barry J, Martinez, Fernando J, McCormack, Meredith C   +12 more
core   +1 more source