Results 71 to 80 of about 124,570 (215)

Role of Dual-Specificity Phosphatase 1 in Glucocorticoid-Driven Anti-inflammatory Responses

Frontiers in Immunology, 2019
Glucocorticoids (GCs) potently inhibit pro-inflammatory responses and are widely used for the treatment of inflammatory diseases, such as allergies, autoimmune disorders, and asthma. Dual-specificity phosphatase 1 (DUSP1), also known as mitogen-activated
Jessica Hoppstädter, Alaina J. Ammit, Alaina J. Ammit   +2 more
doaj   +1 more source

Functional Characterization of a Porcine Emphysema Model

, 2013
Lung emphysema is a central feature of chronic obstructive pulmonary disease (COPD), a frequent human disease worldwide. Cigarette smoking is the major cause of COPD, but genetic predisposition seems to be an important factor.
Nielsen, Jens, Cirera, Susanna, Jørgensen, Claus Bøttcher, Bruun, Camilla Vibeke Sichlau, Leifsson, Páll S., Leifsson, Páll Skuli, Johansen, Louise Kruse, Jensen, Henrik Elvang, Fredholm, Merete, Bruun, Camilla Sichlau, Cirera Salicio, Susanna, Jensen, Louise Kruse   +11 more
core   +1 more source

Immediate Resumption of Positive Airway Pressure Following Sinus Surgery: A Prospective Controlled Multicenter Study

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Untreated obstructive sleep apnea (OSA) in the perioperative period confers significant cardiopulmonary risk. However, many otolaryngologists defer restarting positive airway pressure (PAP) therapy following functional endoscopic sinus surgery (FESS) due to perceived risk of epistaxis, mucosal injury, and wound healing.
Garret Choby, Jose L. Mattos, Erin K. O'Brien, Devyani Lal, Michael J. Marino, Spencer Payne, Carlos N. Pinheiro‐Neto, Nicholas R. Rowan, Anthony Tang, Eric W. Wang, Janalee Stokken   +10 more
wiley   +1 more source

Representation of EPCs levels with extent of emphysema on log-log scale by emphysema subtype.

, 2017
Lines represent modelling results after adjustment for age, gender, race/ethnicity, cohort, smoking status, pack-years, educational attainment, body mass index, height, diabetes mellitus, hypertension, oxygen saturation, white blood cell count, sleep ...
Russell P. Tracy (127552), Katja Hueper (185428), Jens Vogel-Claussen (313462), Margaret F. Doyle (449942), Megha A. Parikh (3836458), Karol Watson (405670), Steven Kawut (3836449), Daichi Shimbo (301599), Joao Lima (235647), R. Graham Barr (109958), Eric A. Hoffman (109953), Antoinette Gomes (3836455), Benjamin M. Smith (3836452), John H. M. Austin (546978)   +13 more
core   +1 more source

Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema

BMC Pulmonary Medicine, 2005
Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte ...
Marchal Joëlle, Leçon-Malas Véronique, Boutten Anne, Bonay Marcel, Soler Paul, Fournier Michel, Leseche Guy, Dehoux Monique, Crestani Bruno   +8 more
doaj   +1 more source

Clinical Outcomes and Acute Exacerbation Incidence in Combined Pulmonary Fibrosis and Emphysema

Respirology, EarlyView.
This multicentre prospective study of 1016 patients demonstrated that CPFE, defined as ≥ 5% emphysema on visual CT assessment, identified a high‐risk phenotype with significantly worse 5‐year survival compared to non‐CPFE IIP patients (51.4% vs. 63.1%) and COPD patients (51.4% vs. 84.0%) and higher acute exacerbation incidence, validating international
Kazuya Tsubouchi, Yasuaki Kotetsu, Tomotsugu Takano, Hiroaki Ogata, Fumiaki Kiyomi, Katsuyuki Ichiki, Shohei Takata, Yasuhiko Kitasato, Hiroshi Ishii, Kazuhiro Yatera, Kei Yamasaki, Masaki Okamoto, Makoto Yoshida, Masayuki Kawasaki, Masaki Fujita, Tomohiro Ogawa, Kazunori Tobino, Eiji Harada, Noriaki Nakagaki, Masashi Komori, Taishi Harada, Hiroshi Wataya, Yoichi Nakanishi, Isamu Okamoto   +23 more
wiley   +1 more source

High prevalence of bronchiectasis in emphysema-predominant COPD patients

, 2018
Shuang Dou,1 Chunyan Zheng,1 Liwei Cui,1 Mengshuang Xie,1 Wei Wang,1 Hui Tian,1 Kang Li,1 Kaidi Liu,1 Xinyu Tian,1 Xin Wang,1 Qun Zhang,1 Xin Ai,1 Junchao Che,1 Qixiao Liu,1 Haijun Li,2 Wei Xiao1 1Department of Pulmonary Medicine, Qilu Hospital ...
Li H, Liu K, Cui L, Tian H, Xie M, Liu Q, Xiao W, Che J, Li K, Zhang Q, Dou S, Tian X, Zheng C, Wang W, Wang X, Ai X   +15 more
core  

Prediction of Total Lung Capacity and Residual Volume Eligibilities for Endobronchial Valve Treatment Using Measurements by the Helium Dilution Technique, CT‐Based Lung Volume Analysis, and Spirometry

Respirology, EarlyView.
When body plethysmography is not feasible, helium dilution and CT volumetry, alone or combined with spirometry, may provide practical alternatives to help identify patients likely or unlikely to meet plethysmography‐defined eligibility criteria for endobronchial valve treatment.
Daisuke Kinose, Yasutaka Nakano, Masamichi Mineshita   +2 more
wiley   +1 more source

Lung Emphysema & Cardiac Function [PDF]

, 2008
Patients with severe lung emphysema have poor quality of life because of impaired lung function and reduced exercise tolerance. Concomitant heart disease in severe emphysema is well recognised.
Jörgensen, Kirsten
core   +1 more source

Progress in Explosion Mechanisms and Prevention Technologies for Direct Chill Casting Aluminum Melt Upon Water Contact: A Review

Safety Science and Technology, EarlyView.
Molten aluminum–water explosion triggered by leakage remains the core unresolved safety hazard hindering safe production in aluminum direct chill casting. This review summarizes its explosion mechanism, key influencing factors, prevention technologies, existing gaps, and prospects of intelligent multi‐technology integrated explosion‐proof systems ...
Min Wang, Kang Yang, Jiang Dong, Lidong Xing, Bing Chen, Changke Chen   +5 more
wiley   +1 more source