Results 81 to 90 of about 218,651 (379)

Effect and Mechanism of Running on Mouse Emphysema Model Induced by Cigarette Extract

康复学报, 2022
ObjectiveTo observe the effect of running on mouse emphysema model induced by cigarette extract, and to explore its mechanism based on signal transducer and activator of transcription 3 (STAT3).MethodsA total of 40 male C57BL/6 mice were randomly divided
LI Yongrong, XIE Haibin, LI hong, SUN Jie   +3 more
doaj  

Treatment of Advanced Emphysema with Emphysematous Lung Sealant (AeriSeal (R)) [PDF]

, 2011
Background: This report summarizes initial tests of an emphysematous lung synthetic polymer sealant (ELS) designed to reduce lung volume in patients with advanced emphysema.
A. Ernst, Argenziano M, B. Schmidt, D. Gompelmann, de Oliveira HG, F. Stanzel, F.J.F. Herth, Fessler HE, Geiser T, H. Magnussen, Hopkinson NS, Ingenito EP, J. Behr, Keenan RJ, Macklem PT, R. Bonnet, R. Eberhardt   +16 more
core   +1 more source

Emphysema [PDF]

The Boston Medical and Surgical Journal
n ...
openaire   +1 more source

Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema

Respiratory Research, 2018
BackgroundMitochondrial damage leading to oxidant stress may play an important role in the pathogenesis of airflow obstruction and emphysema. NLPR3 inflammasome can be activated by mitochondrial ROS (mtROS) and other stimuli.
Feng Li, Mengmeng Xu, Muyun Wang, Lei Wang, Han-Yue Wang, Hai Zhang, Yuqing Chen, J. Gong, J. Zhang, I. Adcock, K. Chung, Xin Zhou   +11 more
semanticscholar   +1 more source

Functional Pulmonary Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The aging of the world population gave rise to an increased prevalence of many lung diseases, with chronic obstructive pulmonary disease now ranking as the third‐leading cause of death according to the World Health Organization. To diagnose lung disease, a thorough assessment of lung function is essential since it may reveal unique signatures ...
Agilo L. Kern, Filip Klimeš, Andreas Voskrebenzev, Hoen‐Oh Shin, Jens Vogel‐Claussen   +4 more
wiley   +1 more source

Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema

BMC Pulmonary Medicine, 2005
Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte ...
Marchal Joëlle, Leçon-Malas Véronique, Boutten Anne, Bonay Marcel, Soler Paul, Fournier Michel, Leseche Guy, Dehoux Monique, Crestani Bruno   +8 more
doaj   +1 more source

Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema. [PDF]

, 2007
Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema.
Chris J. Armit, David J. Harrison, Linda Wilson, Mark Marsden, Rehab J. Al-Jamal, Steven D. Shapiro, Susan McIntyre   +6 more
core   +1 more source

Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

, 2016
BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been ...
Bourne, Simon, Coombs, Ngaire A., Elkington, Paul T., Estepar, Raul San Jose, Harden, Stephen, Kim, Viktoriya, Ostridge, Kristoffer, Staples, Karl J., Washko, George, Wilkinson, Tom M.A., Williams, Nicholas   +10 more
core   +1 more source

Magnetic Resonance Imaging in the Clinical Evaluation of Lung Disorders: Current Status and Future Prospects

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The low proton density and high signal decay rate of pulmonary tissue have previously hampered the application of magnetic resonance imaging (MRI) in the clinical evaluation of lung disorders. With the continuing technical advances in scanners, coils, pulse sequences, and image postprocessing, pulmonary MRI can provide structural and ...
Linyu Wu, Chen Gao, Ting Wu, Ning Kong, Ziwei Zhang, Jie Li, Li Fan, Maosheng Xu   +7 more
wiley   +1 more source

Alpha-1 antitrypsin deficiency [PDF]

, 2001
α-1 antitrypsin is synthesised in the liver and protects lung alveolar tissues from destruction by neutrophil elastase. α-1 antitrypsin deficiency is a common autosomal recessive condition (1:1600 to 1:1800) in which liver disease results from retention ...
Primhak, R.A., Tanner, M.S.
core   +2 more sources