Results 111 to 120 of about 1,043,884 (276)

Strategies to improve work discipline: Analysis of compensation, non-physical work environment, and training in a multibusiness companies in Gresik

open access: yesJournal of Management Small and Medium Enterprises (SME's)
This study investigates the influence of compensation, non-physical work environment, and training on employee work discipline within a multi-business company located in Gresik.
Luluk Syarofaddina Eldianty   +1 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

The Effect of Discipline and Work Environment on Employee Performance in Pelanja Sejahtera

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the influence of Discipline and Work Environment on Employee Performance at PT. Laksana Sejahtera. The study uses a quantitative method with an associative approach, using primary data obtained from 60 employees of PT. Laksana
Suci Rahayu Kartini, Cecep Haryoto
doaj  

THE INFLUENCE OF WORK DISCIPLINE AND TRAINING ON EMPLOYEE PERFORMANCE MEDIATED BY ORGANIZATIONAL COMMITMENT IN PERUMDA AIR MINUM TIRTA SEWAKADARMA DENPASAR [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences
The decline in company performance in terms of service aspects is due to suboptimal employee performance, highlighting the need to focus on factors that can influence employee performance.
Bhagaskara S.I.P.   +2 more
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

PENGARUH MOTIVASI DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN BIRO PEMELIHARAAN BANGUNAN DAN INSTALASI SEKRETARIAT JENDERAL DPR-RI

open access: yesMIX: Jurnal Ilmiah Manajemen, 2015
: The research was conducted to identify and analyze the effect of Motivation and Work Discipline to Employee Performance of Biro Pemeliharaan Bangunan dan Instalasi Sekretariat Jenderal DPR-RI.
Lis Andayani
doaj  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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