Results 91 to 100 of about 336,164 (308)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Gambaran Disiplin Kerja dan Kompensasi Berpengaruh pada Kepuasan Kerja Karyawan Pdam Tirta Berkah Kabupaten [PDF]

open access: yes, 2016
Purpose: This study is to obtain findings regarding: Overview of labor discipline in the Regional Water Company PDAM Tirta Blessing Pandeglang, description of compensation for employees of PDAM Tirta Blessing Pandeglang, description of employee job ...
Afriyady, M. A. (Moch)   +1 more
core  

PENGARUH KEPEMIMPINAN, KEDISIPLINAN DAN MOTIVASI KERJA TERHADAP PRODUKTIVITAS MELALUI KINERJA KARYAWAN (Studi Empiris Pada Perusahaan Daerah Perkebunan (PDP) Kabupaten Jember)

open access: yesJurnal Ekonomi Akuntansi dan Manajemen, 2015
Halil1, Bagus P. Yudhia K.2, Tanti Kustiari2 1 Mahasiswa Program Studi Agribisnis Program Pascasarjana Magister Terapan Politeknik Negeri Jember. 2 Dosen Pascasarjana Magister Terapan Politeknik Negeri Jember. Alamat: Jl. Mastrip, Jawa Timur 68101,
Halil Halil   +2 more
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Pengaruh Motivasi, Disiplin, Lingkungan Dan Kemampuan Terhadap Kinerja Karyawan [PDF]

open access: yes, 2014
Kimia Farma focuses on improving the quality of community life, especially in terms of health and the environment. Semarang Plant, Particularly producing jatropha oil, vegetable oil, and cosmetics (powder). The purpose of research is to determine the
Listyorini, S. (Sari)   +2 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Analisis Pengaruh Gaya Kepemimpinan Partisipatif, Motivasi Dan Disiplin Kerja Terhadap Kinerja Pegawai Pada Pt. Bank Bukopin Tbk. Cabang Klaten [PDF]

open access: yes, 2016
This study aims to determine how the influence of participatory leadership style, motivation and discipline the performance of employees of PT. Bank Bukopin Tbk. Klaten branch. The subjects were employees of PT. Bank Bukopin Tbk. Klaten branch as much as
, Basworo Dibyo, S.E., M.Si   +1 more
core  

A DETERMINATION OF EMPLOYEE PERFORMANCE BASED ON LEADERSHIP STYLE, DISCIPLINE, AND WORK CULTURE ON MOTIVATION AS AN INTERVENING VARIABLE

open access: yesIJEBD (International Journal of Entrepreneurship and Business Development)
Purpose:knowing and analyzing the influence of leadership style on motivation, the influence of work discipline on motivation, the influence of work culture on motivation, the influence of leadership style, discipline, and work culture on motivation ...
eni rosita
doaj   +1 more source

Pengaruh Lingkungan, Disiplin dan Motivasi Kerja Terhadap Kinerja Karyawan PT. Pati Sari Di Aceh Tamiang

open access: yesJKBM (Jurnal Konsep Bisnis dan Manajemen), 2019
This study aims to determine the effect of environment, discipline and work motivation on employee performance at PT. Pati Sari Desa Selamat Kec. Tenggulun Kab. Aceh Tamiang. The number of samples as respondents used was 119 people.
Syardiansah Syardiansah   +1 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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