Results 121 to 130 of about 9,658 (260)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Trends in employee performance: A comprehensive review and bibliometric analysis using Scopus and WOS

open access: yesSA Journal of Human Resource Management
Orientation: Interest in understanding the factors that drive employee performance has increased. However, existing research on the effects of leadership styles and employee engagement lacks conclusive results.
Al Montaser Mohammad   +5 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

MULTICOMPONENT ASSESSMENT OF EMPLOYEE ADAPTATION LEVEL IN THE CORPORATE ENVIRONMENT

open access: yesStudia Universitatis Moldaviae: Stiinte ale Educatiei
The article focuses on the development and application of the Adaptation Coefficient (AC) to assess employees’ integration into the corporate environment, considering their engagement, loyalty, and stress levels.
USM ADMIN
doaj  

Can employees' trust their supervisor? The role of high-performance work systems and stewardship climate on employee voice. [PDF]

open access: yes
The focus of this research is to investigate the factors that influence employee voice behaviour by examining the integration of high-performance work systems, stewardship climate, and trust in supervisor.
Karadas, Georgiana   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Onboarding - Integration of new employees

open access: yes, 2018
Demographic changes, a growing mobility of employees as well as changing values, needs and expectations trigger a so-called “war for talent” and indicate the need to shift from traditional recruiting approaches to more customer-oriented approaches. Permanent changes and developments result in elevated expectations on the part of companies which puts ...
openaire   +1 more source

Does the Emotional Labor of the Service Employee Affect the Self-concept of the Consumer in Service Organization? [PDF]

open access: yes
In service interactions the management of service employee’s emotion through emotional labor has gained prominence and is becoming an active method to affect consumer’s behavior. Several researches have indicated that self-concept of the consumer affects
Mishra, Sushanta Kumar
core  

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