Results 41 to 50 of about 571,930 (311)

Suggestion systems: a usability-based evaluation model [PDF]

open access: yes, 2010
Usability has been used to design and assess products and websites. This paper takes the concept of usability one step further and proposes a framework to assess suggestion systems.
Aburas, H   +3 more
core  

Assessing Leadership and Employee Safety Participation in Managing Health And Safety: A Case Study Of K-Refinery And Petrochemical Companies (K-RPC) [PDF]

open access: yes, 2015
The ever increasing need for energy resources creates complex health and safety challenges in petroleum and petrochemical companies and human participation is crucial to the management of health and safety particularly in K-Refinery and Petrochemical ...
Shaibu, J.H.   +1 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Organizational Renewal: The Management of Large-Scale Organizational Change in Norwegian Firms [PDF]

open access: yes, 1994
A study of large organizational change projects was done in 228 private and public sector firms across Norway to examine the causes and consequences of renewal efforts and the strategies used by firm level management and union leaders to involve the ...
Hammer, Tove H.   +3 more
core   +2 more sources

Job Satisfaction and Quality Management: An Empirical Analysis [PDF]

open access: yes, 2012
Purpose – Quality management requires increasing employee involvement that could empower employees, leading to employee and customer satisfaction.
de Menezes, L. M.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Works Councils and Environmental Investment: Theory and Evidence from German Panel Data [PDF]

open access: yes, 2002
Firms may underinvest in local environmental protection even from the private viewpoint of its owners and employees, but works councils may help mitigate this problem. We show that increases in environmental investments when councils are present could be
Askildsen, Jan Erik   +2 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Employee financial participation in businesses: Is it worth discussing? [PDF]

open access: yes, 2014
This paper is an overview of the achievements in the area of employee financial participation (EFP) during the last fifty years. It addresses the question of the extent to which EFP is relevant in today's world. EFP is distinguished from participation in
Blaszczyk, Barbara
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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