Results 31 to 40 of about 571,930 (311)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Investigating the effect of participatory management with a macro-ergonomics approach on organizational productivity through the mediating variable employee empowerment and participation )case study: General Directorate of Technical and Vocational Training of Fars Province( [PDF]

open access: yesطب کار
Introduction: By directly affecting the environment and creating employee satisfaction, ergonomics creates quality products or services, organizational productivity, and customer satisfaction.
Naser Sadra Abarghoei   +3 more
doaj  

Budgetary participation and performance mediated by work satisfaction and engagement at Timor-Leste

open access: yesContabilidad y Negocios: Revista del Departamento Académico de Ciencias Administrativas
Budgetary participation is paramount in organizational management since it has a direct impact on operations efficacy and the organization success. At Timor-Leste, where managerial practices are still being developed, budgetary participation can be ...
Marta Guterres   +1 more
doaj   +1 more source

Active engagement of managers in employee RTW and manager-employee relationship: managers’ experiences of participating in a dialogue using the Demand and Ability Protocol

open access: yesDisability and Rehabilitation, 2022
To describe how managers of employees on sick-leave, due to chronic pain conditions, experience participating in a three-party meeting using the Demand and Ability Protocol (DAP) in the return-to-work process. This study is based on individual semi-structured interviews with 17 managers of employees with chronic pain.
Katarina Aili   +4 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An evaluation of the basic requirements for the implementation of Total Quality Management at Rasoul Akram Hospital, Tehran, Iran

open access: yesPayesh, 2004
Objective(s): To determine requirements for implementation of a total quality management system at Rasoul Akram Hospital. Methods: This cross-sectional study was conducted in 2003.
Delgoshaei B, Maleki M.R, Dehnavieh R
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Telework within the Bureau of Reclamation Lower Colorado Region office

open access: yes, 2011
A team of researchers from The University of Nevada, Las Vegas were invited by management to observe, assess, and offer recommendations. It was determined by the research team that the first step to improving participation would be to observe the ...
Arnold, Lynne   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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