Results 121 to 130 of about 941,032 (307)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Analyzing the Effect of Work Life Conflict and Job Stress on Employee Performance (Study at the Main Office of PT. Bank Sulutgo) [PDF]

open access: yes, 2016
Employee is one of the important part of the company. Some part that will run the strategy of the company in order to achieving goal is employee. The performance of company can be seen by the positive achievement of the employee.
Lalu, S. E. (Steffany)   +1 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

PENGARUH KEPUASAN KERJA, LINGKUNGAN KERJA DAN MOTIVASI KERJA TERHADAP KINERJA KARYAWAN DI DIVISI INDUSTRIAL DAN ENERGI PT HASKONING INDONESIA

open access: yesMIX: Jurnal Ilmiah Manajemen, 2015
Abstrack: The purpose of this study is to analyze the effect of job satisfaction, work environment and work motivation and its impact on the employee performance.
Yumi Meirina
doaj  

Relationship Between Compensation, Work Environment, Organizational Culture, and Employee Performance at Hotel Sedona Manado [PDF]

open access: yes, 2013
The Indonesian people have more problems in the future human resource development or more specifically on improving the quality of human resources in the current era globalization.
Golung, H. D. (Hana)
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Work Motivation and Compensation on Employee Performance

open access: yesPhilanthropy: Journal of Psychology
This study aims to analyze the effect of work motivation and compensation on employee performance at Percetakan Sewelas Triwulan. The research employs a quantitative approach with an associative design, involving 32 employees selected through a ...
Tri Amindrawati   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

THE INFLUENCE OF WORK BALANCE, WORK DISCIPLINE, AND EMPLOYEE MOTIVATION ON EMPLOYEE PERFORMANCE OF AUTOMOTIVE CARS IN PALOPO CITY

open access: yesJournal of Management Small and Medium Enterprises (SME's)
This study aims to investigate the effect of work balance, work discipline, and employee motivation on the performance of Palopo city car automotive employees. The method used in this research is a quantitative method.
Nurhayani Nurhayani   +2 more
doaj   +1 more source

Influence Communication, Work and Discipline of the Education Level on Employee Performance at PT. Fruit Oil (SBS) District. Kinali, Kab. West Pasaman [PDF]

open access: yes, 2014
The formulation of the issues raised in this study is "The Effect of Communication And Work Discipline Against Employee Job Performance". The variables of this study are: Communication, Work Discipline and level of education (as independent variables ...
Fauzan, F. (Fauzan)   +2 more
core  

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