Results 71 to 80 of about 20,279 (262)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Fostering innovation through green HRM: The mediating role of organizational support and green commitment

Asian Management and Business Review
This study aims to investigate the role of green human resource management (GHRM) on innovative work behavior in helping organizations to implement environmentally friendly business practices.
Ani Yunaningsih, Ahmad Johan, Rima Rahmayanti   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Employee Green Behaviors: A Meta-Analysis

, 2022
Ian M. Katz, Rachel S. Rauvola, Cort W. Rudolph, Hannes Zacher   +3 more
openalex   +2 more sources

How Environmental Knowledge Management Promotes Employee Green Behavior: An Empirical Study [PDF]

, 2021
Wenyao Zhang, Wenyao Zhang, Ruzhi Xu, Yuan Jiang, Wei Zhang, Wei Zhang   +5 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Can environmental transformational leadership shape organizational citizenship behavior toward the environment in Indonesia?

Asian Management and Business Review
This research examines the influence of environmental transformational leadership on organizational citizenship behavior toward the environment. In testing this relationship, other aspects were involved, including green human resources management, a ...
Diah Retno Wulandaru, Anidah Binti Robani, Zaqiah Vivi Putri   +2 more
doaj   +1 more source

Environmentally Specific Servant Leadership and Employees’ Pro-Environmental Behavior: Mediating Role of Green Self Efficacy

Psychology Research and Behavior Management, 2022
Muhammad Farhan Mughal,1 Shuang Li Cai,1 Naveed Ahmad Faraz,2 Fawad Ahmed3 1Department of Business Management, Tianj in University of Finance and Economics, Tianjin, People’s Republic of China; 2School of Management, Hunan University, Changsha, Hunan ...
Mughal MF, Cai SL, Faraz NA, Ahmed F
doaj  

How to facilitate employees' green behavior? The joint role of green human resource management practice and green transformational leadership. [PDF]

Front Psychol, 2022
Chen T, Wu Z.
europepmc   +1 more source