Results 61 to 70 of about 950,753 (317)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
New Employees Benefit Guide: Plan Year 2013
, 2012 This is a new employees benefit and retirement plan guide for employees of the state of Texas for ...
Employees Retirement System of Texas
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
, 2018 Guide for former elected officials, former legislative employees, and former board members during fall enrollment, describing insurance benefits, various insurance offers, prescription drug coverage, and other relevant ...
Employees Retirement System of Texas
core
JPH RECODE (Journal of Public Health Research and Community Health Development)Background: Single Male Migrants (SMMs) are highly vulnerable and at high risk of acquiring and spreading sexually transmitted infections (STIs) due to a lack of social support networks, unstable legal status, cultural and language barriers, high ...
M Shashi Kumar +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2019 Guide for former elected officials, former legislative employees, and former board members during summer enrollment, describing insurance benefits, various insurance offers, prescription drug coverage, and other relevant ...
Employees Retirement System of Texas
core
Quality of life as a predictor of work ability of employees of Sarajevo Tobacco Factory
Journal of Health Sciences, 2016 Introduction: Our aim was to evaluate quality of life (QOL) as a predictor of work abilities of employees in a tobacco factory. Methods: The study was performed in the period between 2011 and 2012. The sample comprised of 270 workers, males and females,
Enisa Sljivo +2 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source