Results 81 to 90 of about 3,219,697 (365)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
BMC Cancer, 2019 Background Eribulin mesylate is a nontaxane microtubule dynamics inhibitor approved for second-line (European Union) or third-line (United States) treatment of metastatic breast cancer.
Lee Schwartzberg +7 more
doaj +1 more source
Dormant Ties: Out of Sight, But Not Out of Mind [PDF]
, 2015 KEY FINDINGS * Dormant ties have a strong effect on an employee\u27s organizational commitment. In contrast to employees’ active relationships, which can be time consuming to maintain and result in stress at higher levels, the benefits of dormant ties do
McCarthy, John
core +1 more source
THE EMPLOYEE PERFORMANCE ASSESSMENT AND EMPLOYEE TRAINING, ON EMPLOYEE INTENSION
JURNAL APLIKASI MANAJEMEN, 2019 This study aims to examine and analyze the effect of employee performance appraisal and employee learning, to an employee out intentions with employee retention as a mediating variable. High employee turnover rates can result in negative impacts on the company such as decreasing service, decreasing productivity and resulting in increased human resource
Ignatius Jeffrey, Agus Budi Prasetya
openaire +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Massive pericardial effusion in undiagnosed turner syndrome [PDF]
Anesthesia and Pain Medicine, 2023 Divya Sethi Sethi, Garima Garg
doaj +1 more source
Sentra PM (a Medical Food) and Trazodone in the Management of Sleep Disorders
Journal of Central Nervous System Disease, 2012 Sleep disorders are a common and poorly treated disease state. This double blind, four arm placebo-controlled, randomized trial compared (1) low dose trazodone, (2) Sentra PM, a neurotransmitter based medical food, (3) the joint administration of ...
William E. Shell Md +4 more
doaj +1 more source
EMPLOYEE RECRUITMENT AND PLACEMENT PROCESS STRATEGY USING STRENGTH BASED ASSESSMENT
, 2023 Cuk Jaka Purwanggono
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Examining of the Effects of Employees on Work Stress, Role Conflict and Job Insecurity on Organizational Culture [PDF]
, 2019 Perceived work stress, It is stated that employees are psychologically disturbed and intensely threatening their health at their busy working tempo. Employees with a high degree of stress in the face of excessive workloads may experience burnout and ...
Adiguzel, Z. (Zafer) +1 more
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