Results 201 to 210 of about 1,592,470 (309)

Workplace Accommodations and Employment Outcomes Among Employees With Autism: A Systematic Review. [PDF]

Cureus
Heinze C.
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Empowering hands and fostering employment: training individuals with spinal cord injury for careers in the beauty industry. [PDF]

Brain Spine
europepmc   +1 more source

Impact of bariatric surgery on monthly earnings and employment: a national linked data study in England, 2014-2022. [PDF]

Int J Obes (Lond)
Bermingham CR, Ayoubkhani D, Zaccardi F, Coulman KD, Valabhji J, Khunti K, Pournaras DJ, Santos R, Islam N, Razieh C, Dolby T, Nafilyan V.   +11 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Mapping food access: how neighborhood deprivation shapes healthy food availability in the United Kingdom. [PDF]

BMC Public Health
Beydoun MA, Georgescu MF, Banerjee S, Beydoun HA, Noren Hooten N, Khubchandani J, Maldonado AI, Tsai J, Weiss J, Evans MK, Zonderman AB.   +10 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Social inclusion of people with severe mental illness: a review of current practices, evidence and unmet needs, and future directions. [PDF]

World Psychiatry
Henderson C, Kotera Y, Lloyd-Evans B, Jordan G, Gorner M, Salla A, Kalha J, Coventry PA, Bojke L, Hinde S, Slade M.   +10 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A Social Return on Investment Evaluation of the Expansion of an Allied Health Student Training Programme in Rural Australia. [PDF]

Aust J Rural Health
French L, Lander C, Green E, Nott M, Anderson G, Brusco NK.   +5 more
europepmc   +1 more source