Results 61 to 70 of about 314,024 (302)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
What Can We Learn from Disability Enterprises When Thinking About a Job Guarantee Program?
DisabilitiesThe Disability Royal Commission in Australia has reinforced concerns that segregated employment settings can increase risks of exploitation, violence and abuse, including within Australian Disability Enterprises (ADEs), strengthening the case for ...
Andrew Joyce +3 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Understanding the meaning of politicisation of hte employment relationship through historical analysis [PDF]
, 2010 For more than one hundred years, Australian governments have supported the principle that the employment relationship of public servants should be independent of direct control by politicians.
Haidar, A, Spooner, KB
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Supported Employment Programmes for People With Psychosis or Schizophrenia – Full Cycle Audit
BJPsych OpenAims Our aim was to see if the following have been done during medical reviews: 1.For service users with a diagnosis of psychosis or schizophrenia; is there clear documentation of employment status in case notes?
Mounika Iderapalli +2 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Brain and BehaviorObjective To explore the efficiency of IPS on employment, education, and training (EET) outcomes in young adults with early psychosis. Methods Monocenter parallel arm, randomized controlled trial.
Dorothea Jäckel +6 more
doaj +1 more source
Supported employment interventions in LMIC.
, 2023 ObjectiveTo review the evidence of supported employment interventions in low-to-middle income countries, documents their impact for persons with mental disorders in the open labour market and well as support decision making for its wider implementation ...
Clement Nhunzvi (14769202) +2 more
core +1 more source