Results 71 to 80 of about 347,402 (318)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Search for a theoretical focus : human resource management or employment relations?

, 2002
This article argues that the human resource management perspective is insufficient as a framework within which to explain the employment relationship. Following the discussion of the limitations of the HRM perspective, the article considers alternative ...
Leece, Priscilla, Mortimer, Dennis E.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

International Review of Performance Management Systems in Public Employment Services

, 2010
This report presents the findings from a literature review which explores how other Public Employment Services (PES) across Europe use performance measurement in support of their organisational objectives in order that Jobcentre Plus can learn from this ...
Mitchell, B, Nunn, Alex, Mitchell, Ben, Bickerstaffe, Tim, Nunn, A, Bickerstaffe, T   +5 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Profiling in aviation : its effects on employment

, 2005
This paper will discuss the potential introduction into Australian aviation of passenger profiling, and its flow-on effects. Focusing on its applicability in other domains such as employment.
Stewart, Gordon, Watson, Genevieve, Glambedakis, Antony, Mortimer, Dennis E.   +3 more
core  

Understanding the meaning of politicisation of hte employment relationship through historical analysis [PDF]

, 2010
For more than one hundred years, Australian governments have supported the principle that the employment relationship of public servants should be independent of direct control by politicians.
Haidar, A, Spooner, KB
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Small retailers and employment regulation : is deregulation really necessary?

, 2005
This paper examines the responses of small retailing businesses to the deregulation of industrial relations and the question as to whether these businesses regard employment regulation/deregulation as necessary to the more efficient conduct of their ...
Whiting, Elizabeth, Wilkinson, Fiona, Stewart, Gordon, Bond, Sue, Mortimer, Dennis E.   +4 more
core  

Workplace Industrial Relations Survey, 1990

, 1992
copyright UK Data Service and data collection copyright owner. The Workplace Industrial Relations Survey (WIRS) series was designed to contribute to a better understanding of the processes which underlie employment relationships by making available ...
Policy Studies Institute, Employment Department, Employment Market Research Unit   +1 more
core   +1 more source