Results 81 to 90 of about 1,256,698 (342)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Legal Implications of Constitutional Court Decision 168/PUU-XXI/2023 on Employment Termination within Islamic Political Jurisprudence

open access: yesHakamain
This research examines the legal implications of Constitutional Court Decision No. 168/PUU-XXI/2023 on employment termination, analysed through the framework of Islamic political jurisprudence (siyasah dusturiyyah).
Kanaya Tabita   +2 more
doaj   +1 more source

Termination of Employment

open access: yesAlberta Law Review, 1972
If as Parliamentary critics would have us believe, more and more Canadians are soon to become "consumers of social services", Professor Harrison's article is indeed timely. In the following pages one aspect of the law of master and servant is explored—that of termination of employment.
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Tales of IT Consultants: Understanding Psychological Contract Maintenance and Employment Termination

open access: yesAustralasian Journal of Information Systems, 2015
This research investigates the question why dedicated Information Technology (IT) consultants quit their jobs and voluntarily terminate their employment contracts.
K. Kautz, Gro Bjerknes
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

China Employment Law Update - October 2009 [PDF]

open access: yes, 2009
[Excerpt] The Beijing High Court and the Beijing Municipal Labor Dispute Arbitration Committee jointly announced through meeting minutes issued in August 2009 several clarifications on key employment issues.
Baker & McKenzie
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Problems Affecting Labor [PDF]

open access: yes, 1944
Much experimental work has been devoted in comparing the folding behavior of proteins sharing the same fold but different sequence. The recent design of proteins displaying very high sequence identities but different 3D structure allows the unique ...
Brunori, M.   +5 more
core   +5 more sources

Company Policy on Termination of Employment at Pandemic Covid-19 From a Fair and Justice Perspective

open access: yesProceedings of the 2nd International Conference of Law, Government and Social Justice (ICOLGAS 2020), 2020
--Currently the spread of the Covid-19 Virus develops rapidly not only in Indonesia but almost all over the world, before the new normal applied by the government, almost most cities in Indonesia implemented a large-scale social restriction (hereinafter ...
Prawitra Thalib   +4 more
semanticscholar   +1 more source

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