Results 51 to 60 of about 124,240 (288)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The Concept of Emptiness and Accompanying Concepts in the Philosophical Analysis of Madhyamaka
Ars & Humanitas, 2022 The article analyses the concept of emptiness (śūnyatā) of the Buddhist Mahāyāna school Madhyamaka. By way of introduction, some fundamental questions are asked regarding the possible meaning of that concept as well as the possible context within which ...
Goran Kardaš
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Empty Selves and Multiple Belonging: Gadamer and Nāgārjuna on Religious Identity’s Hidden Plurality
Open Theology, 2017 The reaction to multiple religious belonging has been fraught with anxiety in the monotheistic traditions. Nevertheless, increasing numbers of people report belonging to multiple religions.
Hustwit J. R.
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Asian StudiesThis article explores the concept of “nothingness” in the Advaita Vedānta and Madhyamaka traditions of Indian Buddhism, analysing their convergences, divergences, and broader implications within Indian philosophical traditions.
Pankaj Vaishnav
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Distinguishing Emptiness from Nothingness
Asian StudiesThe philosophical definition of the relationship between nothingness and emptiness continues to spark academic debates and controversies. In this article, we aim to clarify this relationship by examining some Chinese discourses relevant to the topic. The
Jana S. Rošker
doaj +1 more source
Language Emptiness of Continuous-Time Parametric Timed Automata
, 2015 Parametric timed automata extend the standard timed automata with the possibility to use parameters in the clock guards. In general, if the parameters are real-valued, the problem of language emptiness of such automata is undecidable even for various ...
Aleksandra Jovanović +14 more
core +1 more source
A remark on the subleading order in the asymptotics of the nonequilibrium emptiness formation probability [PDF]
, 2010 We study the asymptotic behavior of the emptiness formation probability for large spin strings in a translation invariant quasifree nonequilibrium steady state of the isotropic XY chain.
Aschbacher, Walter H.
core +5 more sources