Results 61 to 70 of about 124,240 (288)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
On the Chacteristic Numbers of Voting Games [PDF]
This paper deals with the non-emptiness of the stability set for any proper voting game.We present an upper bound on the number of alternatives which guarantees the non emptiness of this solution concept.
Mathieu Martin, Vincent Merlin
core +3 more sources
Why Is Virtual Reality Interesting for Philosophers?
Frontiers in Robotics and AI, 2018 This article explores promising points of contact between philosophy and the expanding field of virtual reality research. Aiming at an interdisciplinary audience, it proposes a series of new research targets by presenting a range of concrete examples ...
Thomas K. Metzinger, Thomas K. Metzinger
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Kriterion, 2011 O artigo reconstrói alguns momentos salientes do desenvolvimento das doutrinas do 'não-si' e das 'duas verdades' na história da filosofia buddhista, desde as formulações originárias do buddhismo de base, às conclusões alcançadas por Nāgārjuna ...
Giuseppe Ferraro
doaj +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
, 2013 The Deficiency-One Theorem states that there exists a unique positive steady state in each positive stoichiometric class for weakly reversible deficiency-one mass action systems with one linkage class (regardless of the values of the rate coefficients ...
Boros, Balázs
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Simple Priorities and Core Stability in Hedonic Games [PDF]
In this paper we study hedonic games where each player views every other player either as a friend or as an enemy. Two simple priority criteria for comparison of coalitions are suggested, and the corresponding preference restrictions based on ...
Dinko Dimitrov, Peter Borm
core +3 more sources