Results 41 to 50 of about 372,613 (338)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Switched Energy Management Strategy for Fuel Cell Hybrid Vehicle Based on Switch Network
Energies, 2020 Environmentally friendly and pollution-free fuel cell/lithium battery hybrid vehicles have received the attention of the community in recent years. It is imperative for fuel cell/lithium battery hybrid vehicles to use the energy management strategy (EMS)
Xu Chen +4 more
doaj +1 more source
Saudi Journal of Emergency Medicine, 2023 Background Emergency Medical Services (EMS) have been always considered as a vital service provided by of many Red Cross and Red Crescent (RCRC) national societies worldwide and in Middle East and North Africa (MENA) region in particular during emergency
Haytham Qosa, Mohamed Rashad Abdelaziz
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Water Quality Research Journal, 2021 This paper builds on previous research to address the question of whether there is practical value for a made-in-Ontario municipal management system standard (MSS) for wastewater and stormwater related activities, in addition to the Drinking Water ...
Edgar Tovilla
doaj +1 more source
AF-EMS Detector: Improve the Multi-Scale Detection Performance of the Anchor-Free Detector [PDF]
, 2021 Jiangqiao Yan +4 more
openalex +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Effect of induced mutagenesis in M1 and M2 generations of cumin (Cuminum cyminum L.)
Electronic Journal of Plant Breeding, 2023 Cumin is an important spice that has been used for centuries in various cuisines around the world. Two cumin varieties (GC 3 and GC 4) were subjected to mutation to understand macromutational modifications.
H. N. Patel1*, M. P. Patel2, N. V. Soni1, N. B. Patel1, A. M. Patel3 and N. I. Patel4
doaj +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source