Results 91 to 100 of about 213,806 (248)

Anomalous Spin‐Optical Helical Effect in Ti‐Based Kagome Metal

Advanced Materials, EarlyView.
The kagome lattice hosts diverse correlated quantum states, including elusive loop currents. We report spin‐handedness selective signals in CsTi3Bi5, termed the anomalous spin‐optical helical effect, surpassing conventional spin responses. Arising from light helicity coupled to spin‐orbital correlations, this effect provides a sensitive, indirect probe
Federico Mazzola, Wojciech Brzezicki, Chiara Bigi, Armando Consiglio, Luciano Jacopo D'Onofrio, Maria Teresa Mercaldo, Adam Kłosiński, François Bertran, Patrick Le Fèvre, Oliver J. Clark, Mark T. Edmonds, Manuel Tuniz, Alessandro De Vita, Vincent Polewczyk, Jeppe B. Jacobsen, Henrik Jacobsen, Jill A. Miwa, Justin W. Wells, Anupam Jana, Ivana Vobornik, Jun Fujii, Niccolo Mignani, Narges Tarakameh Samani, Alberto Crepaldi, Giorgio Sangiovanni, Anshu Kataria, Tommaso Morresi, Samuele Sanna, Pietro Bonfá, Brenden R. Ortiz, Ganesh Pokharel, Stephen D. Wilson, Domenico Di Sante, Carmine Ortix, Mario Cuoco   +34 more
wiley   +1 more source

EMT Program is Dispensable for Metastasis but Induces Chemoresistance in Pancreatic Cancer

Nature, 2015
Diagnosis of pancreatic ductal adenocarcinoma (PDAC) is associated with a dismal prognosis despite current best therapies; therefore new treatment strategies are urgently required. Numerous studies have suggested that epithelial-to-mesenchymal transition
Xiaofeng Zheng, Julienne L. Carstens, Jiha Kim, Matthew Scheible, Judith Kaye, H. Sugimoto, Chia-Chin Wu, Valerie S. LeBleu, R. Kalluri   +8 more
semanticscholar   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Agile manipulation of the time-frequency distribution of high-speed electromagnetic waves

Nature Communications
Controlling the temporal evolution of an electromagnetic (EM) wave’s frequency components, the so-called time-frequency (TF) distribution, in a versatile and real-time fashion remains very challenging, especially at the high speeds (> GHz regime ...
Xinyi Zhu, Benjamin Crockett, Connor M. L. Rowe, Hao Sun, José Azaña   +4 more
doaj   +1 more source

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

EMBO Reports, 2008
The embryonic programme ‘epithelial–mesenchymal transition’ (EMT) is thought to promote malignant tumour progression. The transcriptional repressor zinc‐finger E‐box binding homeobox 1 (ZEB1) is a crucial inducer of EMT in various human tumours, and was ...
U. Burk, Jörg Schubert, U. Wellner, O. Schmalhofer, E. Vincan, S. Spaderna, T. Brabletz   +6 more
semanticscholar   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Data-Aided Maximum Likelihood Joint Angle and Delay Estimator Over Orthogonal Frequency Division Multiplex Single-Input Multiple-Output Channels Based on New Gray Wolf Optimization Embedding Importance Sampling

Sensors
In this paper, we propose a new data-aided (DA) joint angle and delay (JADE) maximum likelihood (ML) estimator. The latter consists of a substantially modified and, hence, significantly improved gray wolf optimization (GWO) technique by fully integrating
Maha Abdelkhalek, Souheib Ben Amor, Sofiène Affes   +2 more
doaj   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Fabrication Error Modeling and Analysis of an E-Band MHMIC Balanced Power Detector

IEEE Access
This study models and analyses the fabrication errors of an ultra-wideband (UWB) Schottky diode power detector using miniature hybrid-microwave integrated-circuit (MHMIC) technology.
Mehrdad Harifi-Mood, Nima Souzandeh, Peyman PourMohammadi, Djilali Hammou, Bryan Hosein, Sonia Aissa, Serioja Ovidiu Tatu   +6 more
doaj   +1 more source

Guided-Wave Properties of Mode-Selective Transmission Line

IEEE Access, 2018
The so-called mode-selective transmission line or simply “MSTL” is studied theoretically and experimentally. This low-loss and low-dispersion transmission line operates with a frequency-dependent mode-switching behavior.
Faezeh Fesharaki, Tarek Djerafi, Mohamed Chaker, Ke Wu   +3 more
doaj   +1 more source