Results 61 to 70 of about 366,025 (373)
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Why Effective Medium Theory Fails in Granular Materials
, 1999 Experimentally it is known that the bulk modulus, K, and shear modulus, \mu, of a granular assembly of elastic spheres increase with pressure, p, faster than the p^1/3 law predicted by effective medium theory (EMT) based on Hertz-Mindlin contact forces ...
A. V. Tkachenko +21 more
core +1 more source
TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy [PDF]
, 2010 Background/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis.
Hills, Claire E., Squires, Paul E.
core +1 more source
EMT and Anti-EMT Strategies in Cancer
Journal of Cancer Therapy, 2015 This article discusses the role of epithelial mesenchymal transition (EMT) and addresses the scientific merits on epigenetic regulation of EMT. The importance of EMT as a prognostic biomarker is explored and the rationale on application of multitargeted epigenetic therapy is discussed. We describe a literature review of the epigenetic influence of such
M. A. Nezami +2 more
openaire +2 more sources
Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT
Biomolecules, 2021 Recent advances in our understanding of the molecular pathways that control the link of inflammation with organ fibrosis and autoimmune diseases point to the epithelial to mesenchymal transition (EMT) as the common association in the progression of these
M. Sisto, D. Ribatti, S. Lisi
semanticscholar +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Genetic algorithm-enhanced microcomb state generation
Communications PhysicsMicrocavities enable the generation of highly efficient microcombs, which find applications in various domains, such as high-precision metrology, sensing, and telecommunications.
Celine Mazoukh +10 more
doaj +1 more source
Spectrally resolved wave-mixing between near- and far-infrared pulses in gas
New Journal of Physics, 2013 We investigate the nonlinear wave-mixing in gases between intense, short optical pulses and long-wavelength fields (mid infrared and terahertz). We show numerically that the beating between the sum- and difference-frequency generation components can be ...
M Clerici +10 more
doaj +1 more source
EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration
International Journal of Molecular Sciences, 2020 Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT) are physiological processes required for normal embryogenesis. However, these processes can be hijacked in pathological conditions to facilitate tissue fibrosis and ...
Daisy Y. Shu +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source