Results 71 to 80 of about 366,025 (373)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
APL Photonics, 2018 We present a novel class of CMOS-compatible devices aimed to perform the solid-state-biased coherent detection of ultrashort terahertz pulses, i.e., featuring a gap-free bandwidth at least two decades-wide.
A. Tomasino +9 more
doaj +1 more source
Sensors, 2019 We propose a new collaborative beamforming (CB) solution robust (i.e., RCB) against major channel estimation impairments over dual-hop transmissions through a wireless sensor network (WSN) of K nodes. The source first sends its signal to the WSN.
Oussama Ben Smida +3 more
doaj +1 more source
Increasing appropriate social communication and pragmatic language skills in young adults with autism spectrum disorders [PDF]
, 2016 This report seeks to explore intervention methodologies that can be adapted for use with young transitional adults with Autism Spectrum Disorders (ASD) to increase appropriate social communication.
Coppock, Amanda Rene'
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Anti-EMT and anti-fibrosis effects of protocatechuic aldehyde in renal proximal tubular cells and the unilateral ureteral obstruction animal model [PDF]
, 2022 Yu-Teng Chang +5 more
openalex +1 more source
The 'alternative' EMT switch [PDF]
Breast Cancer Research, 2011 Epithelial to mesenchymal transition (EMT) is an essential process in embryonic development and is aberrantly induced in many disease settings. Work carried out by Chonghui Cheng's laboratory addressed the involvement of alternative RNA splicing in EMT and its link to tumour progression. They describe a switch in CD44 expression from variant isoform(s)
Klingbeil, Pamela, Isacke, Clare M
openaire +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
IEEE AccessDeep neural network (DNN) classifiers are potent instruments that can be used in various security-sensitive applications. Nonetheless, they are vulnerable to certain attacks that impede or distort their learning process.
Orson Mengara +2 more
doaj +1 more source
Tumor Budding: The Name is EMT. Partial EMT. [PDF]
Journal of Clinical Medicine, 2016 Tumor budding is a histological phenomenon encountered in various cancers, whereby individual malignant cells and/or small clusters of malignant cells are seen in the tumor stroma. Postulated to be mirror epithelial-mesenchymal transition, tumor budding has been associated with poor cancer outcomes.
Alexandru Grigore +4 more
openaire +3 more sources