Results 71 to 80 of about 338,860 (400)
Kidney International, 2005 Epithelial-mesenchymal transition (EMT) is a process whereby epithelial cell layers lose polarity and cell-cell contacts and undergo a massive cytoskeleton reorganization involving the rho family and the remodeling of the actin microfilament mesh (Thiery, 2002).
openaire +1 more source
Association of the Epithelial–Mesenchymal Transition (EMT) with Cisplatin Resistance
International Journal of Molecular Sciences, 2020 Therapy resistance is a characteristic of cancer cells that significantly reduces the effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent, which is widely used in the treatment of various types of cancer ...
M. Ashrafizadeh +6 more
semanticscholar +1 more source
Energy momentum tensor and the D-term in the bag model [PDF]
Phys. Rev. D 101, 034013 (2020), 2019 The energy-momentum tensor (EMT) form factors pave new ways for exploring hadron structure. Especially the D-term related to the EMT form factor D(t) has received a lot of attention due to its attractive physical interpretation in terms of mechanical properties.
arxiv +1 more source
EMT Program is Dispensable for Metastasis but Induces Chemoresistance in Pancreatic Cancer
Nature, 2015 Diagnosis of pancreatic ductal adenocarcinoma (PDAC) is associated with a dismal prognosis despite current best therapies; therefore new treatment strategies are urgently required. Numerous studies have suggested that epithelial-to-mesenchymal transition
Xiaofeng Zheng +8 more
semanticscholar +1 more source
IEEE Journal of Translational Engineering in Health and Medicine, 2017 The last few years has seen a proliferation of wearable electrocardiogram (ECG) devices in the market with applications in fitness tracking, patient monitoring, athletic performance assessment, stress and fatigue detection, and biometrics, to name a few.
Diana P. Tobon +2 more
doaj +1 more source
Investigating Epithelial-To-Mesenchymal Transition with Integrated Computational and Experimental Approaches [PDF]
, 2019 The transition between epithelial and mesenchymal (EMT) is a fundamental cellular process that plays critical roles in development, cancer metastasis, and tissue wound healing. EMT is not a binary process but involves multiple partial EMT states that give rise to a high degree of cell state plasticity.
arxiv +1 more source
Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution. [PDF]
, 2019 Elucidating the spectrum of epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) states in clinical samples promises insights on cancer progression and drug resistance.
Anchang, Benedict +8 more
core
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Transport in a highly asymmetric binary fluid mixture [PDF]
, 2006 We present molecular dynamics calculations of the thermal conductivity and viscosities of a model colloidal suspension with colloidal particles roughly one order of magnitude larger than the suspending liquid molecules.
G. K. Batchelor +6 more
core +2 more sources
JCI Insight, 2020 SGLT2 inhibitors are beneficial in halting diabetic kidney disease; complete mechanisms is unknown. The epithelial to mesenchymal transition (EMT) is associated with Sirt3 suppression and aberrant glycolysis.
Jinpeng Li +8 more
semanticscholar +1 more source