Results 101 to 110 of about 22,476 (217)

Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors

open access: yesPPAR Research, 2010
Peroxisome proliferator-activated receptors (PPARs) are members of a steroid hormone receptor superfamily that responds to changes in lipid and glucose homeostasis.
Tengis S. Pavlov   +2 more
doaj   +1 more source

Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.

open access: yesPLoS ONE, 2010
BackgroundThe epithelial sodium channel (ENaC) is an integral component of the pathway for Na(+) absorption in epithelial cells. The ubiquitin ligases Nedd4 and Nedd4-2 bind to ENaC and decrease its activity.
Dominik Wiemuth   +6 more
doaj   +1 more source

Mechanical Strain-Mediated Tenogenic Differentiation of Mesenchymal Stromal Cells Is Regulated through Epithelial Sodium Channels

open access: yesStem Cells International, 2020
It has been suggested that mechanical strain may elicit cell differentiation in adult somatic cells through activation of epithelial sodium channels (ENaC). However, such phenomenon has not been previously demonstrated in mesenchymal stromal cells (MSCs).
Hui Yin Nam   +5 more
doaj   +1 more source

Central Role for ENaC in Development of Hypertension [PDF]

open access: yesJournal of the American Society of Nephrology, 2005
Na(+) reabsorption by the epithelial Na(+) channel (ENaC) in cortical collecting duct provides the final renal adjustment to Na(+) balance, there being no further downstream Na(+) transport system. This fact coupled with the responsiveness of ENaC to aldosterone, which conveys stimulation inversely proportional to the state of Na(+) balance, places ...
openaire   +2 more sources

Substructure in the ENACS clusters

open access: yes, 1998
Subclustering is investigated in a set of 67 rich cluster galaxy samples extracted from the ESO Nearby Abell Cluster Survey (ENACS) catalog. We apply four well-known statistical techniques to evaluate the frequency with which substructure occurs. These diagnostics are sensitive to different aspects of the spatial and velocity distribution of galaxies ...
Solanes, J. M.   +2 more
openaire   +2 more sources

Cl– Interference with the Epithelial Na+ Channel ENaC

open access: yes, 2005
The cystic fibrosis transmembrane conductance regulator (CFTR) is a protein kinase A and ATP-regulated Cl- channel that also controls the activity of other membrane transport proteins, such as the epithelial Na+ channel ENaC.
Voelcker, Thilo   +5 more
core   +1 more source

ENaC is a host susceptibility factor to bacterial infections in cystic fibrosis context

open access: yesCommunications Biology
Cystic fibrosis (CF) is a genetic disease caused by dysfunction in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) chloride channel. Patients with CF are hypersusceptible to Mycobacterium abscessus infection, a fast-growing mycobacterium ...
Hamadoun Touré   +7 more
doaj   +1 more source

Modelling interactive computing systems: Do we have a good theory of what computers are?

open access: yesZagadnienia Filozoficzne w Nauce, 2022
Computers are increasingly interactive. They are no more transformational systems producing a final output after a finite execution. Instead, they continuously react in time to external events that modify the course of computing execution.
Alice Martin   +2 more
doaj  

Upregulation of the WNK4 Signaling Pathway Inhibits Epithelial Sodium Channels of Mouse Tracheal Epithelial Cells After Influenza A Infection

open access: yesFrontiers in Pharmacology, 2019
Influenza virus has a significant impact on the respiratory system. The mechanism of how influenza virus impairs the fluid transport in airway is not fully understood. We examined its effects on epithelial sodium channels (ENaC), which are very important
Yapeng Hou   +8 more
doaj   +1 more source

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