Results 111 to 120 of about 34,637 (221)

Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors

open access: yesPPAR Research, 2010
Peroxisome proliferator-activated receptors (PPARs) are members of a steroid hormone receptor superfamily that responds to changes in lipid and glucose homeostasis.
Tengis S. Pavlov   +2 more
doaj   +1 more source

The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC

open access: yesBMC Research Notes, 2010
Background Epithelial cells are exposed to a variety of mechanical stimuli. Epithelial Na+ channels (ENaC) mediate sodium transport across apical membranes of epithelial cells that line the distal nephron, airway and alveoli, and distal colon.
Ilatovskaya Daria V   +2 more
doaj   +1 more source

Mechanical Strain-Mediated Tenogenic Differentiation of Mesenchymal Stromal Cells Is Regulated through Epithelial Sodium Channels

open access: yesStem Cells International, 2020
It has been suggested that mechanical strain may elicit cell differentiation in adult somatic cells through activation of epithelial sodium channels (ENaC). However, such phenomenon has not been previously demonstrated in mesenchymal stromal cells (MSCs).
Hui Yin Nam   +5 more
doaj   +1 more source

Protein Kinase D1 Modulates Aldosterone-Induced ENaC Activity in a Renal Cortical Collecting Duct Cell Line [PDF]

open access: yes, 2010
Aldosterone treatment of M1-CCD cells stimulated an increase in epithelial Na+ channel (ENaC) alpha-subunit expression that was mainly localized to the apical membrane.
Dooley, Ruth   +6 more
core   +1 more source

WAVE proteins mediate ENaC activity

open access: yesThe FASEB Journal, 2010
The epithelial Na + channel (ENaC) is an essential channel responsible for Na + reabsorption. Similar to other ion channels, ENaC activity is regulated, in part, by cortical cytoskeleton.
Alexey V Karpushev   +2 more
openaire   +1 more source

Benzamil sensitive ion channels contribute to volume regulation in canine chondrocytes [PDF]

open access: yes, 2012
Background and Purpose: Chondrocytes exist within cartilage and serve to maintain the extracellular matrix. It has been postulated that osteoarthritic (OA) chondrocytes lose the ability to regulate their volume, affecting extracellular matrix production.
Barrett-Jolley, Richard   +7 more
core   +2 more sources

Modelling interactive computing systems: Do we have a good theory of what computers are?

open access: yesZagadnienia Filozoficzne w Nauce, 2022
Computers are increasingly interactive. They are no more transformational systems producing a final output after a finite execution. Instead, they continuously react in time to external events that modify the course of computing execution.
Alice Martin   +2 more
doaj  

New era of cystic fibrosis: full mutational analysis and personalized therapy [PDF]

open access: yes, 2017
Despite its apparently simple genetics, cystic fibrosis (CF) is a rather complex genetic disease. A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator (CFTR ) gene to the clinical manifestations ...
Lucarelli, Marco
core   +1 more source

Uncertainty visualization of gaze estimation to support operator-controlled calibration

open access: yesJournal of Eye Movement Research, 2018
In this paper, we investigate how visualization assets can support the qualitative evaluation of gaze estimation uncertainty. Although eye tracking data are commonly available, little has been done to visually investigate the uncertainty of recorded gaze
Almoctar Hassoumi   +2 more
doaj   +1 more source

Upregulation of the WNK4 Signaling Pathway Inhibits Epithelial Sodium Channels of Mouse Tracheal Epithelial Cells After Influenza A Infection

open access: yesFrontiers in Pharmacology, 2019
Influenza virus has a significant impact on the respiratory system. The mechanism of how influenza virus impairs the fluid transport in airway is not fully understood. We examined its effects on epithelial sodium channels (ENaC), which are very important
Yapeng Hou   +8 more
doaj   +1 more source

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