Results 21 to 30 of about 34,637 (221)
Complex evolutionary dynamics of massively expanded chemosensory receptor families in an extreme generalist chelicerate herbivore [PDF]
, 2016 While mechanisms to detoxify plant produced, anti-herbivore compounds have been associated with plant host use by herbivores, less is known about the role of chemosensory perception in their life histories.
Bajda-Wybouw, Sabina +10 more
core +4 more sources
High glucose up-regulates ENaC and SGK1 expression in HCD-cells [PDF]
, 2006 Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately ...
Bell LM +30 more
core +1 more source
ENaC–Membrane Interactions [PDF]
The Journal of General Physiology, 2004 Recently, it was reported that the epithelial Na+ channel (ENaC) is regulated by temperature (Askwith, C.C., C.J. Benson, M.J. Welsh, and P.M. Snyder. 2001. Proc. Natl. Acad. Sci. USA. 98:6459–6463). As these changes of temperature affect membrane lipid order and lipid–protein interactions, we tested the hypothesis that ENaC activity can be modulated ...
Mouhamed S. Awayda +4 more
openaire +1 more source
Frontiers in Immunology, 2017 Previous in vitro studies have indicated that tumor necrosis factor (TNF) activates amiloride-sensitive epithelial sodium channel (ENaC) current through its lectin-like (TIP) domain, since cyclic peptides mimicking the TIP domain (e.g., solnatide ...
Anita Willam +18 more
doaj +1 more source
Intact cytoskeleton is required for small G protein dependent activation of the epithelial Na+ channel. [PDF]
PLoS ONE, 2010 BACKGROUND: The Epithelial Na(+) Channel (ENaC) plays a central role in control of epithelial surface hydration and vascular volume. Similar to other ion channels, ENaC activity is regulated, in part, by cortical cytoskeleton.
Alexey V Karpushev +4 more
doaj +1 more source
Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis [PDF]
, 2018 We sought to decipher the mechanisms underlying the kidney's response to changes in K+ load and intake, under physiological and pathophysiological conditions.
Edwards, Aurelie +2 more
core +1 more source
Sensing and Bio-Sensing Research, 2020 Epithelial sodium channel (ENaC) is a protein that has a central role in the development of hypertension. ENaC is a transmembrane protein that overexpressed in arterial hypertension patients.
Yeni Wahyuni Hartati +5 more
doaj +1 more source
Requirements for cabin crew medical examinations and assessments [PDF]
, 2015 The aim of the current study is to review current regulations relatively to medical requirements necessary to achieve suitability to fly of the cabin crew. There are three classes of flight crew medical standards and licensing. A first class medical
Di Folco, Francesco +3 more
core +1 more source
Proteases, ENaCs and cystic fibrosis [PDF]
The Journal of Physiology, 2014 Airway epithelia maintain a fluid cushion supporting a mucous layer that traps inhaled particulates. This fluid layer facilitates ciliary beating that propels mucus out of the airway. The height of this fluid cushion is carefully regulated by balancing rates of fluid secretion mediated by the cystic fibrosis transmembrane conductance regulator (CFTR ...
Thomas R, Kleyman, Michael M, Myerburg
openaire +2 more sources
Pharmacological Modulation of Ion Channels for the Treatment of Cystic Fibrosis
Journal of Experimental Pharmacology, 2021 Madalena C Pinto,1,* Iris AL Silva,1,* Miriam F Figueira,2 Margarida D Amaral,1 Miquéias Lopes-Pacheco1,* 1Biosystems & Integrative Sciences Institute (BioISI), Faculty of Sciences, University of Lisboa, Lisboa, Portugal; 2Marsico Lung ...
Pinto MC +4 more
doaj