Results 31 to 40 of about 22,476 (217)
Mechanism of Fluid Reabsorption in Kidney Proximal Tubule: Interplay Between Lateral Na<sup>+</sup>/K<sup>+</sup>-ATPase and AQP1 and SGLT1 Mediated Water Fluxes. [PDF]
Acta Physiol (Oxf)ABSTRACT Aims The mechanism of isosmotic water reabsorption in the kidney proximal tubule, with a focus on the interaction between the lateral Na+/K+‐ATPase, apical water pathways mediated by AQP1 and SGLT1, and paracellular water flow through Claudin‐2. Methods A mathematical model of proximal tubular transport was used to compute coupled ion, solute,
Larsen EH, Sørensen JN.
europepmc +2 more sources
Proteases, ENaCs and cystic fibrosis [PDF]
The Journal of Physiology, 2014 Airway epithelia maintain a fluid cushion supporting a mucous layer that traps inhaled particulates. This fluid layer facilitates ciliary beating that propels mucus out of the airway. The height of this fluid cushion is carefully regulated by balancing rates of fluid secretion mediated by the cystic fibrosis transmembrane conductance regulator (CFTR ...
Thomas R, Kleyman, Michael M, Myerburg
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Journal of Pharmacological Sciences, 2022 Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in the world, and has no radical treatment. Inhibition of amiloride-sensitive epithelial sodium ion channel (ENaC) has now been considered as a potential therapeutic ...
Ryunosuke Nakashima +14 more
doaj +1 more source
ENaC activity in collecting ducts modulates NCC in cirrhotic mice. [PDF]
, 2015 Cirrhosis is a frequent and severe disease, complicated by renal sodium retention leading to ascites and oedema. A better understanding of the complex mechanisms responsible for renal sodium handling could improve clinical management of sodium retention.
Beatrice, Rohrbach +19 more
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Cellular Physiology and Biochemistry, 2018 Background/Aims: The epithelial sodium channel (ENaC) in cortical collecting duct (CCD) principal cells plays a critical role in regulating systemic blood pressure.
Yu-Jia Zhai +11 more
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Scientific Reports, 2021 Activity of the Epithelial Na+ Channel (ENaC) in the distal nephron fine-tunes renal sodium excretion. Appropriate sodium excretion is a key factor in the regulation of blood pressure.
Tarek Mohamed Abd El-Aziz +7 more
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Assessment of the CFTR and ENaC association [PDF]
Molecular BioSystems, 2008 Abstract Cystic fibrosis (CF) is one of the most common lethal genetic disorders. It results primarily from mutations in the cystic fibrosis transmembrane conductance regulator (cftr) gene. These mutations cause inadequate functioning of CFTR, which in turn leads to the severe disruption of transport function in several epithelia ...
Bakhrom K, Berdiev +2 more
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Nanosatellite activities at ENAC: the TETX receiving ground station and the EYESAT mission control center [PDF]
, 2018 International audienceThis paper describes the activities of ENAC (École Nationale de l’Aviation Civile), Toulouse, around the nanosatellites. Firstly, the TETX (Telemetry Earth Terminal X‐band) receiving antenna and itsaccompanying satellite signal ...
Brochet, Philippe +2 more
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Landscape of ENaC regulation in the kidney [PDF]
American Journal of Physiology-Renal Physiology, 2012 as the real estate maxim goes, “There are three things that matter in property: location, location, location.” The same could be said about epithelial Na+ channel (ENaC) regulation in the mouse kidney.
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Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC
Molecular Brain, 2019 This study describes the functional interaction between Cav3.2 calcium channels and the Epithelial Sodium Channel (ENaC). β-ENaC subunits showed overlapping expression with endogenous Cav3.2 calcium channels in the thalamus and hypothalamus as detected ...
Agustin Garcia-Caballero +7 more
doaj +1 more source