Results 51 to 60 of about 22,476 (217)
ENaCs and ASICs as therapeutic targets
American Journal of Physiology-Cell Physiology, 2012 The epithelial Na+ channel (ENaC) and acid-sensitive ion channel (ASIC) branches of the ENaC/degenerin superfamily of cation channels have drawn increasing attention as potential therapeutic targets in a variety of diseases and conditions. Originally thought to be solely expressed in fluid absorptive epithelia and in neurons, it has become apparent ...
Yawar J, Qadri +2 more
openaire +3 more sources
, 2002 Members of the ENaC/degenerin family of ion channels include the epithelial sodium channel (ENaC), acid-sensing ion channels (ASICs) and the nematode Caenorhabditis elegans degenerins. These channels are activated by a variety of stimuli such as ligands (
Gautschi, I. +5 more
core +1 more source
α-ENaC expression in the renal medulla.
, 2020 A1. Representative Western Blot analysis of α-ENaC (78 kDa) and tubulin (50 kDa) in homogenates of the renal medulla. A2. α-ENaC protein expression indicated as α-ENaC /tubulin ratio fold change from CNS rats. B.
Carlos Davio (705605) +8 more
core +1 more source
Formal Approach to Safety‐Driven Dynamic Procedure Modeling
Systems Engineering, EarlyView.ABSTRACT Ensuring the safety of unmanned aerial systems (UAS) is a growing concern as the number of UAS grows increasingly fast. Regulatory bodies are in the process of tackling this problem by issuing standards and recommendations to be met by UAS designers.
Jean‐Charles Chaudemar +3 more
wiley +1 more source
Inhibition of ENaC by Endothelin-1 [PDF]
, 2015 The amiloride-sensitive epithelial Na(+) channel (ENaC) is a key player in the regulation of Na(+) homeostasis. Its functional activity is under continuous control by a variety of signaling molecules, including bioactive peptides of endothelin family.
Andrey, Sorokin, Alexander, Staruschenko
openaire +2 more sources
The Cagliari Airport impact on Sardinia tourism: a Logit-based analysis
, 2012 In the field of air transportation management, traditionally, airlines have been the main actors in the process for deciding which new flights open in a given airport, while airports acted only as the managers of the operations. The changes in the market
Gobbato, Luca +4 more
core +1 more source
BMC Genetics, 2007 Background To test whether epithelial sodium channel (ENaC) genes' variants contribute to salt sensitive hypertension in Dahl rats, we screened ENaC α, β, and γ genes entire coding regions, intron-exon junctions, and the 3' and 5' flanking regions in ...
Leenen Frans HH +2 more
doaj +1 more source
Veterinary Clinical Pathology, EarlyView.Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey +2 more
wiley +1 more source
The Role of α-ENaC and δ-ENaC in Breast Cancer Cell Migration [PDF]
, 2019 Breast cancer is an important disease worldwide, primarily affecting women, and is the most common and deadliest form of female cancer. This is reflected in New Zealand’s population as breast cancer has high incidence and mortality rates. In New Zealand,
Ambalawanar, Hiroki
core +1 more source
NUVOLE DI PUNTI - FRA SCANSIONE LASER E IMAGING DI PROSSIMITÀ QUALCHE CONSIDERAZIONE E RIFLESSIONE
GEOmedia, 2016 The article deals with the automatic survey techniques which collect point clouds over the objects of interest. It ranges from laser scanning to survey for images, that is having meaningful awakenings through the proximity aerial survey after the advent ...
Luigi Colombo
doaj