Results 41 to 50 of about 25,643 (173)
Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
core +1 more source
COMBINED ANTIHYPERTENSIVE THERAPY IN METABOLIC SYNDROME
Рациональная фармакотерапия в кардиологии, 2016 Aim. To compare effects of enalapril in combination with long-acting nifedipine or moxonidine on blood pressure (BP), myocardial mass and diastolic function of left ventricular, lipid and carbohydrate metabolism, platelet aggregation in patients with ...
E. I. Mananko +3 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed +7 more
wiley +1 more source
Análise comparativa da farmacocinética do enalapril e da hidroclorotiazida quando utilizados em formulação isolada e em associação [PDF]
, 2011 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011A associação de medicamentos no tratamento da hipertensão arterial pode, através de efeitos ...
Gomes, Eduardo
core
Biomolecules, 2018 Mitochondrial dysfunction is a relevant mechanism in cardiac aging. Here, we investigated the effects of late-life enalapril administration at a non-antihypertensive dose on mitochondrial genomic stability, oxidative damage, and mitochondrial quality ...
Anna Picca +11 more
doaj +1 more source
CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension
British Journal of Clinical Pharmacology, EarlyView.Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien +7 more
wiley +1 more source
Estudo de preparações líquidas orais pediátricas de maleato de enalapril empregadas na terapia hospitalar da insuficência cardíaca congestiva [PDF]
, 2004 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em Farmácia.Enalapril é um pró-fármaco pertencente à classe dos inibidores da enzima conversora de angiotensina (ECA), cuja forma ...
Mello, Aline Cláudia de
core
Enalapril: new possibilities [PDF]
, 2012 The review presents the modern evidence on new properties of enalapril, which widens our perception of therapeutic effects of this ...
E. O. Taratukhin
core +1 more source
Clinical Nutrition Experimental, 2019 Summary: Enalapril is angiotensin converting enzyme (ACE) inhibitor have been extensively used to treat cardiovascular disorders, including hypertension. Coccinia indica is indigenous plant wildly used in traditional medicinal system including Ayurvedic,
G. Vinothkumar +4 more
doaj +1 more source
A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids
Chemistry – A European Journal, EarlyView.This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci +8 more
wiley +1 more source