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Enantiomer fractions instead of enantiomer ratios [PDF]

Chemosphere, 2000
The use of enantiomer ratios (ERs) to indicate the relative amounts of a pair of enantiomers in a sample has some disadvantages. Enantiomer fractions (EFs) are proposed as all alternative expression to eliminate the difficulties.
Boer, J. de, Brinkman, U.A.T., Geus, H.J. de, Wester, P.G.   +3 more
core   +7 more sources

Synthesis of novel phthalimido oxime pseudoesters and evaluation of their cytotoxicity [PDF]

Journal of the Serbian Chemical Society, 2020
A series of novel optically pure oxime pseudoesters derivatives were synthesized by the reaction of substitute keto oximes with various N-substituted α-amino acids chlorides in the presence of triethylamine and dichloromethane at 0°C, and their ...
Mehrez Asma, Chakroun Ibtissem, Mtat Dalila, Ben Mansour Hédi, Touati Ridha   +4 more
doaj   +1 more source

(±)-Cryptamides A–D, Four Pairs of Novel Dopamine Enantiomer Trimers from the Periostracum Cicadae

Molecules, 2022
Four pairs of novel dopamine enantiomer trimers, (±)-cryptamides A–D (1–4), and 10 pairs of previously described dopamine enantiomer dimers (5–14) were isolated from the Periostracum cicadae, the cast-off shell of the insect Cryptotympana pustulata ...
Junjian Luo, Wenjun Wei, Pan Wang, Tao Guo, Suiqing Chen, Liping Zhang, Shuying Feng   +6 more
doaj   +1 more source

Probing Fast Enantio-Recognition of Drugs with Multiple Chiral Centers by Electrospray-Tandem Mass Spectrometry and Its Mechanism

Applied Sciences, 2022
Chiral drugs are very complex substances since individual enantiomers may differ in pharmacological and toxic effects, making it necessary to analyze enantiomers separately.
Hechen Wang, Xiaolei Chen, Yali Wang, Lu Wang, Zhangzhao Gao, Haihong Hu, Lushan Yu, Su Zeng, Yu Kang   +8 more
doaj   +1 more source

Synthesis of 6-Halo-Substituted Pericosine A and an Evaluation of Their Antitumor and Antiglycosidase Activities

Marine Drugs, 2022
The enantiomers of 6-fluoro-, 6-bromo-, and 6-iodopericosine A were synthesized. An efficient synthesis of both enantiomers of pericoxide via 6-bromopericosine A was also developed.
Yoshihide Usami, Yoshino Mizobuchi, Mai Ijuin, Takeshi Yamada, Mizuki Morita, Koji Mizuki, Hiroki Yoneyama, Shinya Harusawa   +7 more
doaj   +1 more source

Distribution and Quantification of 1,2-Propylene Glycol Enantiomers in Baijiu

Foods, 2021
Enantiomers of 1,2-Propylene glycol (1,2-PG) were investigated in 64 commercial Chinese Baijiu including soy sauce aroma-type Baijiu (SSB), strong aroma-type Baijiu (STB), and light aroma-type Baijiu (LTB), via chiral gas chromatography (β-cyclodextrin).
Hao Xu, Yifeng Dai, Shuyi Qiu, Baoguo Sun, Xiangyong Zeng   +4 more
doaj   +1 more source

Determination of 2-Pentanol Enantiomers via Chiral GC-MS and Its Sensory Evaluation in Baijiu

Foods, 2022
The enantiomeric contents of 2-pentanol of Baijiu were analyzed by liquid-liquid extraction (LLE) coupled with gas chromatography-mass spectrometry (GC-MS) using β-cyclodextrin as a chiral stationary phase.
Lisha Hu, Shuyi Qiu, Yifeng Dai, Luqin Tian, Chaoyang Wei   +4 more
doaj   +1 more source

Systematic Investigations on Continuous Fluidized Bed Crystallization for Chiral Separation

Crystals, 2020
A recently developed continuous enantioseparation process utilizing two coupled fluidized bed crystallizers is systematically investigated to identify essential correlations between different operation parameters and the corresponding process performance
Erik Temmel, Jonathan Gänsch, Andreas Seidel-Morgenstern, Heike Lorenz   +3 more
doaj   +1 more source

Synthesis, Characterization and HPLC Analysis of the (1S,2S,5R)-Diastereomer and the Enantiomer of the Clinical Candidate AR-15512

Molecules, 2021
AR-15512 (formerly known as AVX-012 and WS-12) is a TRPM8 receptor agonist currently in phase 2b clinical trials for the treatment of dry eye. This bioactive compound with menthol-like cooling activity has three stereogenic centers, and its final ...
Sergio Rodríguez-Arévalo, Eugènia Pujol, Sònia Abás, Carles Galdeano, Carmen Escolano, Santiago Vázquez   +5 more
doaj   +1 more source

Two-Dimensional Hetero- to Homochiral Phase Transition from Dynamic Adsorption of Barbituric Acid Derivatives

Nanomaterials, 2023
Barbituric acid derivative (TDPT) is an achiral molecule, and its adsorption on a surface results in two opposite enantiomerically oriented motifs, namely TDPT-Sp and Rp. Two types of building blocks can be formed; block I is enantiomer-pure and is built
Fabien Silly, Changzhi Dong, François Maurel, Xiaonan Sun   +3 more
doaj   +1 more source