Metal‐covalent organic frameworks (MCOFs) are novel porous materials that exhibit the advantages of covalent and metal‐organic frameworks. However, it is extremely difficult to resolve their atomic structure and better understand their structure‐properties relation. This work utilizes a synergistic combination of advanced microscopy, spectroscopic, and
Seán Hennessey +11 more
wiley +1 more source
One-Dimensional 13C NMR Is a Simple and Highly Quantitative Method for Enantiodiscrimination
The discrimination of enantiomers of mandelonitrile by means of 1D 13C NMR and with the aid of the chiral solvating agent (S)-(+)-1-(9-anthryl)-2,2,2-trifluoroethanol (TFAE) is presented.
Peter P. Lankhorst +2 more
doaj +1 more source
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier +10 more
wiley +1 more source
Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1
Oncogenic fusion proteins, such as EWS-FLI1, are excellent therapeutic targets as they are only located within the tumor. However, there are currently no agents targeted toward transcription factors, which are often considered to be 'undruggable.' A ...
Julie +23 more
semanticscholar +1 more source
A molecular motor with four‐state dynamic chirality is integrated into liquid crystals, enabling quadruple sequential helix inversions and high helical twisting power. Due to high motor efficiency, the supramolecular helicity can be controlled by near‐infrared light via upconversion nanoparticles, resulting in a robust, multistate, photoresponsive soft
Jinyu Sheng +3 more
wiley +1 more source
How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones. [PDF]
The origin of selectivity in the α-fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional calculations.
Houk, KN, Lam, Yu-hong
core +2 more sources
Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella +3 more
wiley +1 more source
A Pair of Manganese(III) Schiff-Base Enantiomers: Synthesis, Crystal Structure and Magnetic Characterization [PDF]
Based-on the quasi-planar tetra-dentate Schiff-base ligand, a pair of manganese(III) Schiff-base enantiomers formulated as {[Mn(R,R-3-MeOSalcy)(H2O)(CH3OH)]ClO4}2 (1) and {[Mn(S,S-3-MeOSalcy)(H2O)(CH3OH)]ClO4}2 (2) (3-MeOSalcy = N,N′-(1,2 ...
Hongyan Zhang +2 more
doaj
Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]
Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L., +5 more
core +1 more source
Dynamic Chiral Plasmonic Systems‐Based on Spiropyran Derivatives and Gold Nanorods
Soft chiral plasmonic nanocomposites are prepared by embedding gold nanorods into spiropyran‐based supramolecular gels. The system self‐assembles into helical structures, enabling plasmonic circular dichroism. When illuminated with UV light spiropyran–merocyanine isomerization occurs, inducing reversible nanoscale reorganization and modulation of the ...
Ewelina Tomczyk +4 more
wiley +1 more source

