Results 111 to 120 of about 42,748 (282)

Protein binding of chloroquine enantiomers and desethylchloroquine. [PDF]

open access: bronze, 1986
David Ofori‐Adjei   +3 more
openalex   +1 more source

Enantiomers of Indacrinone [PDF]

open access: yesCardiovascular Drug Reviews, 1985
William B. Abrams   +4 more
openaire   +2 more sources

Isothiourea‐Catalysed Acylative Kinetic and Dynamic Kinetic Resolution of Planar Chiral Paracyclophanols

open access: yesAngewandte Chemie, EarlyView.
The highly selective acylative (dynamic) kinetic resolution of racemic paracyclophanols catalysed by a chiral isothiourea (5 mol%) is described (up to s = 50 at 49% conversion or up to 98:2 er and 96% yield in 30 examples). Rotational barriers were analysed for paracyclophanols and selected ester products.
Zhanyu Zhou   +4 more
wiley   +2 more sources

Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates

open access: yesAngewandte Chemie, EarlyView.
Aziridination of alkenes is an important route to chiral nitrogen‐containing building blocks. We report that carbamate‐functionalized allylic alcohols undergo highly enantioselective aziridination using achiral dimeric Rh complexes ion‐paired with cinchona alkaloid‐derived chiral cations.
Arthur R. Lit   +4 more
wiley   +2 more sources

Hochgradig enantioselektive Organokatalyse mit zweizähnigen Halogenbrückendonoren

open access: yesAngewandte Chemie, EarlyView.
In einer Mukaiyama‐Aldol‐Modellreaktion mit allgemeinen Substraten wurden hohe Enantioselektivitäten mit einem modifizierbaren, bidentaten Iod(I)‐basierten Halogenbrücken‐Organokatalysator erreicht. Die entscheidende Rolle der Halogenbrücken wurde durch das schlechte Abschneiden des entsprechenden Wasserstoffbrückendonors und durch DFT‐Berechnungen ...
Julian Wolf   +6 more
wiley   +1 more source

Shaping of a Reactive Manganese Catalyst Enables Access to Polyfunctionalized Cyclohexanes via Enantioselective C(sp3)─H Bond Oxidation of 1,3‐meso Diethers

open access: yesAngewandte Chemie, EarlyView.
Structural shaping of a highly reactive chiral Mn‐oxo species translates into exceptionally enantioselective C─H oxidation catalyst of cyclohexyl 1,3‐meso diethers (up to >99% ee) leading to polyfunctionalized cyclohexanes. Abstract Chiral polyoxygenated cyclohexanes are valuable constituents of biologically relevant products.
Andrea Palone   +7 more
wiley   +2 more sources

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