Results 121 to 130 of about 107,976 (280)

Terahertz Chiral Recognition Based on Metasurfaces

open access: yesAdvanced Photonics Research, EarlyView.
A novel terahertz chiral sensing method based on a multilayer metallic metasurface is proposed. The left‐handed circularly polarized and right‐handed circularly polarized components in the linearly polarized illuminating light into two focal points and convert them back into linear polarization for convenient measurement.
Xuyang Ji   +5 more
wiley   +1 more source

A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder [PDF]

open access: bronze, 2022
Ewa Galaj   +16 more
openalex   +1 more source

Nanophotonic Strategies for Chiral Biosensing: Nanoparticles, Metasurfaces, Magneto‐Optical, and Quantum Approaches

open access: yesAdvanced Photonics Research, EarlyView.
Recent advances in nanophotonics‐based chiral biosensing approaches are comprehensively reviewed, highlighting key trends, advantages, and limitations of each technology. Special attention is given to emerging strategies that exploit magneto‐optical and quantum plasmonic phenomena to enhance sensitivity down to the level of a few molecules, or even a ...
Jorge Ricardo Mejía‐Salazar
wiley   +1 more source

An Enantiomer of an Oral Small Molecule TSH Receptor Agonist Exhibits Improved Pharmacologic Properties

open access: yesFrontiers in Endocrinology, 2016
We are developing an orally available small molecule, allosteric TSH receptor (TSHR) agonist for follow up diagnostics of patients with thyroid cancer.
Susanne Neumann   +7 more
doaj   +1 more source

Poly-arginine peptide R18D reduces neuroinflammation and functional deficits following traumatic brain injury in the Long-Evans rat [PDF]

open access: yes, 2019
We have previously demonstrated that the poly-arginine peptide R18 can improve histological and functional outcomes following traumatic brain injury (TBI) in the Sprague–Dawley rat.
Anderton, Ryan S   +5 more
core   +1 more source

Influence Spatial Degeneracy on Rotational Spectroscopy Three Wave Mixing and enantiomeric state separation of Chiral Molecules

open access: yes, 2018
Pulse flip angles are calculated for three wave mixing, three state cycles of chiral molecules to produce optimized free induction decay amplitudes proportional to the enantiomeric excess of a sample, and to produced optimized degree of state specific ...
Lehmann, Kevin K.
core   +1 more source

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

open access: yesNature, 2016
Major depressive disorder affects around 16 per cent of the world population at some point in their lives. Despite the availability of numerous monoaminergic-based antidepressants, most patients require several weeks, if not months, to respond to these ...
P. Zanos   +19 more
semanticscholar   +1 more source

Chiral Potassium Brønsted Base‐Catalyzed Stereoselective Synthesis of 1,3‐Diols via a Tandem Allylic Isomerization/Asymmetric Aldol–Tishchenko Reaction

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Chiral potassium base catalysts featuring 1,1´‐bi‐2‐naphthol‐derived chiral crown ethers as ligands promote a tandem allylic isomerization/asymmetric aldol‐Tishchenko reaction of allylic alcohols and aldehydes. This method provides enantioenriched 1,3‐diols with excellent diastereoselectivity and high enantioselectivity, thereby expanding the synthetic
Hiroki Ishikawa, Masahiro Sai
wiley   +1 more source

Analytical Enantio-Separation of Linagliptin in Linagliptin and Metformin HCl Dosage Forms by Applying Two-Level Factorial Design

open access: yesScientia Pharmaceutica, 2016
A novel, stability indicating, reverse phase high-performance liquid chromatography (RP-HPLC) method was developed to determine the S-isomer of linagliptin (LGP) in linagliptin and metformin hydrochloride (MET HCl) tablets (LGP–MET HCl) by implementing ...
Sushant B. Jadhav   +3 more
doaj   +1 more source

The effect of alcohol on the performance of lipase-immobilized enzymatic membrane reactor for esterification of (R,S)-ketoprofen [PDF]

open access: yes, 2006
The effect of alcohols on the performance of lipase-immobilized enzymatic membrane reactor (EMR) for enantioselective esterification of (R,S)-ketoprofen has been studied. In this work, mixed solvent medium was used and the (R)-ketoprofen was reacted with
Bhatia, Subhash   +3 more
core  

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