Results 251 to 260 of about 42,748 (282)
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The Journal of Membrane Biology, 2004
Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol)--which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol--is a unique tool that can be used to better
Emily J. Westover, Douglas F. Covey
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Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol)--which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol--is a unique tool that can be used to better
Emily J. Westover, Douglas F. Covey
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Synthesis of the enantiomer of nelarabine
Tetrahedron Letters, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
John Kitteringham +3 more
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Crystallization of enantiomers
Chemical Engineering and Processing: Process Intensification, 2006Abstract Pure enantiomers are of large interest for several industries. Chemical synthesis is frequently not selective and provides racemic mixtures causing a large interest in efficient separation processes. Preparative chromatography is nowadays a powerful and flexible but expensive technology.
Heike Lorenz +6 more
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Chromatographic separation of enantiomers
Pharmaceutisch Weekblad Scientific Edition, 1988In this paper a review is presented on the chromatographic analysis of enantiomers with special attention to high pressure liquid chromatography. Also, some examples of resolution of racemates by thin layer chromatography and gas chromatography are given.
Karla G. Feitsma, Ben F. H. Drenth
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The Enantiomers: Revolution or Evolution
Current Topics in Medicinal Chemistry, 2001The use of single stereoisomers are gaining popularity in the world of anesthesiology. The reduced costs of production have made these compounds available for clinical application. The majority of drugs used in anesthesiology such as ketamine, isoflurane, etomidate, atracurium, bupivacaine and ropivacaine have an asymmetric carbon, and are still used ...
G Ekatodramis, A Borgeat
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Mutagenicity of Enantiomers of Penbutolol
Drug and Chemical Toxicology, 1989With a view to examine the effect of chirality and the cause of batch-to-batch variation in the mutagenicity of penbutolol, penbutolol enantiomers - isopenbutolol [R(+)-enantiomer] and penbutolol [S(-)-enantiomer] - and two batches of Betapressin were tested employing the Ames Salmonella tester strain TA98. The mutagenic activity of R(+)-enantiomer was
Ahmed A. Al-Dakan +3 more
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An introduction to enantiomers in psychopharmacology
Human Psychopharmacology: Clinical and Experimental, 2001There is growing scientific, clinical, commercial and regulatory recognition that enantiomers offer benefits over racemates in the management of psychiatric diseases as well as in clinical medicine generally. However, relatively few studies consider enantiomers' individual characteristics.
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2001
Symmetry exists in many guises and forms in the natural world and has profound significance to our lives. The concept of symmetry has a broad appeal and so is applied to what we perceive with our senses and right down to the sub atomic level. The Tiger for example has a plane of reflectional symmetry running down the centre of her nose which bisects ...
K.-S. Boos +7 more
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Symmetry exists in many guises and forms in the natural world and has profound significance to our lives. The concept of symmetry has a broad appeal and so is applied to what we perceive with our senses and right down to the sub atomic level. The Tiger for example has a plane of reflectional symmetry running down the centre of her nose which bisects ...
K.-S. Boos +7 more
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Biotransformation of deprenyl enantiomers
European Journal of Drug Metabolism and Pharmacokinetics, 1999Rats were treated with either (-)- or (+)-deprenyl, and the metabolites extracted from the plasma, liver, kidney and heart homogenates were studied by chiral capillary electrophoresis (CE). Stereoselective dealkylation of both optical isomers with the formation of desmethyldeprenyl (DD), methamphetamine (MA), and amphetamine (A) was found.
Huba Kalász, E. Szoko, Kálmán Magyar
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Resolution of aristeromycin enantiomers
Journal of Medicinal Chemistry, 1985L'activite biologique des analogues carbocycliques de l'adenosine et de l'adenosine monophosphate peut etre attribuee exclusivement a la presence de l'enantiomere(−) dans les melanges ...
Hubert Vanderhaeghe +3 more
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