Results 21 to 30 of about 88,128 (341)

Structure of (R,R)-4-bromo-2-{4-[4-bromo-1-(4-toluenesulfonyl)-1H-pyrrol-2-yl]-1,3-dinitrobutan-2-yl}-1-(4-toluenesulfonyl)-1H-pyrrole, another ostensible by-product in the synthesis of geminal-dimethyl hydrodipyrrins

Acta Crystallographica Section E: Crystallographic Communications, 2023
The crystal structure of (R,R)-4-bromo-2-{4-[4-bromo-1-(4-toluenesulfonyl)-1H-pyrrol-2-yl]-1,3-dinitrobutan-2-yl}-1-(4-toluenesulfonyl)-1H-pyrrole (1, C26H24Br2N4O8S2) is presented. The title compound was isolated in suitable yield as a by-product in our
Harry C. Sample, Brendan Twamley, Mathias O. Senge   +2 more
doaj   +1 more source

enantiomer [PDF]

, 2014
Citation: 'enantiomer' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.E02069 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Comparison between Lipase Performance Distributed at the O/W Interface by Membrane Emulsification and by Mechanical Stirring

Membranes, 2021
Multiphase bioreactors using interfacial biocatalysts are unique tools in life sciences such as pharmaceutical and biotechnology. In such systems, the formation of microdroplets promotes the mass transfer of reagents between two different phases, and the
Emma Piacentini, Rosalinda Mazzei, Lidietta Giorno   +2 more
doaj   +1 more source

Cannabis through the looking glass: chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography [PDF]

, 2017
By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ(9)-THC in medicinal marijuana (Bedrocan®).
Cavazzini, A, D'Acquarica, I, Gasparrini, F., Ismail, O, Manzo, C, Mazzoccanti, G, Villani, C, Wilcox, M   +7 more
core   +2 more sources

Alternative Kullback-Leibler information entropy for enantiomers [PDF]

, 2010
In our series of studies on quantifying chirality, a new chirality measure is proposed in this work based on the Kullback-Leibler information entropy.
Borgoo, Alex, Bultinck, Patrick, Geerlings, Paul, Janssens, Sara, Van Alsenoy, Christian   +4 more
core   +2 more sources

The Enantiomer of Allopregnanolone Prevents Pressure-Mediated Retinal Degeneration Via Autophagy

Frontiers in Pharmacology, 2022
In an ex vivo rat ocular hypertension (OHT) model, the neurosteroid allopregnanolone (AlloP) exerts neuroprotective effects via enhancement of both GABAA receptors and autophagy.
Makoto Ishikawa, Makoto Ishikawa, Toru Nakazawa, Toru Nakazawa, Toru Nakazawa, Toru Nakazawa, Hiroshi Kunikata, Hiroshi Kunikata, Kota Sato, Kota Sato, Takeshi Yoshitomi, Takeshi Yoshitomi, Kathiresan Krishnan, Douglas F. Covey, Douglas F. Covey, Douglas F. Covey, Douglas F. Covey, Charles F. Zorumski, Charles F. Zorumski, Charles F. Zorumski, Yukitoshi Izumi, Yukitoshi Izumi, Yukitoshi Izumi   +22 more
doaj   +1 more source

Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors [PDF]

, 2016
Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core   +2 more sources

Enantioseparation Using Cellulose Tris(3,5-dimethylphenylcarbamate) as Chiral Stationary Phase for HPLC: Influence of Molecular Weight of Cellulose

Molecules, 2016
The cellulose oligomers with different degrees of polymerization (DP), 7, 11, 18, 24, 26, 40 and 52, were prepared by hydrolysis of microcrystalline cellulose with phosphoric acid. These oligomers including the starting microcrystalline cellulose (DP 124)
Yuji Okada, Chiyo Yamamoto, Masami Kamigaito, Yuan Gao, Jun Shen, Yoshio Okamoto   +5 more
doaj   +1 more source

A Validated Chiral LC–MS/MS Method for the Enantioselective Determination of (S)-(+)- and (R)-(-)-Ibuprofen in Dog Plasma: Its Application to a Pharmacokinetic Study

Pharmaceutics, 2023
The purpose of this study was to develop a method for simultaneously separating ibuprofen enantiomers using electrospray ionization (ESI) liquid chromatography with tandem mass spectrometry (LC–MS/MS).
Sanghee Choi, Wang-Seob Shim, Jiyoung Yoon, Doowon Choi, Jinseong Lee, Soo-Heui Paik, Eun-Kyoung Chung, Kyung-Tae Lee   +7 more
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Structure and mechanism of acetolactate decarboxylase [PDF]

, 2013
Acetolactate decarboxylase catalyzes the conversion of both enantiomers of acetolactate to the (R)-enantiomer of acetoin, via a mechanism that has been shown to involve a prior rearrangement of the non-natural (R)-enantiomer substrate to the natural (S ...
Anand R., Chan K. K., Collaborative Computational Project Number 4, Crout D. H. G., Crout D. H. G., Crout D. H. G., Crout D. H. G., Crout D. H. G., Dean Rea, DeLano W. L., Dolin M. I., Drake A. F., Dulieu C., Fisher Z., Fusetti F., Gerlt J. A., Hall D. R., Hill R. K., Ho M.-C., Jones T. A., Kabsch W., Løken J. P, Martin Wills, Moen A. R., Murshudov G. N., Najmudin S., Okrasa K., Perrakis A., Read R. J., Robins D. J., Shabir Najmudin, Stritzke K., Størmer F. C., Victoria A. Marlow, Vilmos Fülöp, Vinogradov M., Yan Y.   +36 more
core   +1 more source