Results 21 to 30 of about 107,976 (280)
Dexibuprofen Therapeutic Advances: Prodrugs and Nanotechnological Formulations
Pharmaceutics, 2021 S-(+) enantiomer of ibuprofen (IBU) dexibuprofen (DXI) is known to be more potent than its R-(−) form and exhibits many advantages over the racemic mixture of IBU such as lower toxicity, greater clinical efficacy, and lesser variability in therapeutic ...
Anna Gliszczyńska +1 more
doaj +1 more source
Enantiomeric oxidation of organic sulfides by the filamentous fungi Botrytis cinerea, Eutypa lata and Trichoderma viride [PDF]
, 2007 The biotransformations of a series of substituted sulfides were carried out with the filamentous fungi Botrytis cinerea, Eutypa lata and Trichoderma viride.
Annunziata +28 more
core +2 more sources
Binding and transport of D-aspartate by the glutamate transporter homolog GltTk
eLife, 2019 Mammalian glutamate transporters are crucial players in neuronal communication as they perform neurotransmitter reuptake from the synaptic cleft. Besides L-glutamate and L-aspartate, they also recognize D-aspartate, which might participate in mammalian ...
Valentina Arkhipova +5 more
doaj +1 more source
Alternative Kullback-Leibler information entropy for enantiomers [PDF]
, 2010 In our series of studies on quantifying chirality, a new chirality measure is proposed in this work based on the Kullback-Leibler information entropy.
Borgoo, Alex +4 more
core +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2023 The crystal structure of (R,R)-4-bromo-2-{4-[4-bromo-1-(4-toluenesulfonyl)-1H-pyrrol-2-yl]-1,3-dinitrobutan-2-yl}-1-(4-toluenesulfonyl)-1H-pyrrole (1, C26H24Br2N4O8S2) is presented. The title compound was isolated in suitable yield as a by-product in our
Harry C. Sample +2 more
doaj +1 more source
Field-induced diastereomers for chiral separation [PDF]
, 2019 A novel approach for the state-specific enantiomeric enrichment and the spatial separation of enantiomers is presented. Our scheme utilizes techniques from strong-field laser physics, specifically an optical centrifuge in conjunction with a static ...
Küpper, Jochen +4 more
core +2 more sources
Enantiomer-Specific State Transfer of Chiral Molecules. [PDF]
Physical Review Letters, 2016 State-selective enantiomeric excess is realized using microwave-driven coherent population transfer. The method selectively promotes either R or S molecules to a higher rotational state by phase-controlled microwave pulses that drive electric-dipole ...
S. Eibenberger, J. Doyle, D. Patterson
semanticscholar +1 more source
Membranes, 2021 Multiphase bioreactors using interfacial biocatalysts are unique tools in life sciences such as pharmaceutical and biotechnology. In such systems, the formation of microdroplets promotes the mass transfer of reagents between two different phases, and the
Emma Piacentini +2 more
doaj +1 more source
Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors [PDF]
, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core +2 more sources
Superchiral Surface Waves for All-Optical Enantiomer Separation [PDF]
Journal of Physical Chemistry C, 2018 We introduce the use of superchiral surface waves for the all-optical separation of chiral compounds. Using a combination of electrodynamics modeling and analytical techniques, we show that the proposed approach provides chiral optical forces two orders ...
G. Pellegrini +6 more
semanticscholar +1 more source