Results 31 to 40 of about 88,128 (341)

Effects of α-Melanocortin Enantiomers on Acetaminophen-Induced Hepatotoxicity in CBA Mice

open access: yesMolecules, 2009
Proteins and peptides in mammals are based exclusively on L-amino acids. Recent investigations show that D-amino acids exhibit physiological effects in vivo, despite of their very small quantities. We have investigated the hepatoprotective effects of the
Dražen Vikić-Topić   +8 more
doaj   +1 more source

Total Chiral Symmetry Breaking during Crystallization: Who needs a "Mother Crystal"? [PDF]

open access: yes, 2005
Processes that can produce states of broken chiral symmetry are of particular interest to physics, chemistry and biology. Chiral symmetry breaking during crystallization of sodium chlorate occurs via the production of secondary crystals of the same ...
Cristobal Viedma   +7 more
core   +3 more sources

Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro

open access: yesFrontiers in Pharmacology, 2018
Naftopidil (NAF) is widely used for the treatment of benign prostatic hyperplasia and prevention of prostate cancer in elderly men. These patients receive a combination of drugs, which involves high risk for drug–drug interaction.
Xia-Wen Liu   +9 more
doaj   +1 more source

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]

open access: yes, 2008
Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T.   +5 more
core   +2 more sources

Antiradical and Antibacterial Activity of Essential Oils from the Lamiaceae Family Plants in Connection with their Composition and Optical Activity of Components

open access: yesInternational Journal of Secondary Metabolite, 2018
Antiradical activity of essential oils of korean mint (Agastache rugosa (Fisch. et Mey)), blue giant hyssop (Agastache foeniculum (Pursh) Kuntze), hyssop (Hyssopus officinalis L.), lavander (Lavandula angustifolia L.), peppermint (Mentha piperita L ...
Hanna G. Shutava   +3 more
doaj   +1 more source

Stereochemistry of Simple Molecules inside Nanotubes and Fullerenes: Unusual Behavior of Usual Systems

open access: yesMolecules, 2020
Over the past three decades, carbon nanotubes and fullerenes have become remarkable objects for starting the implementation of new models and technologies in different branches of science.
Valerij Kuznetsov
doaj   +1 more source

A stereo-selective growth inhibition profile of ginsenoside Rh2 on human colon cancer cells

open access: yesCyTA - Journal of Food, 2019
We compared the stereo-selective growth inhibition effects of purified enantiomeric pairs of ginsenoside Rh2 (20(S)-ginsenoside Rh2 and 20(R)-ginsenoside Rh2) on human colon cancer cells in vitro with non-invasive real-time cellular analysis. When 50 μM,
Yunju Jeong   +3 more
doaj   +1 more source

Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]

open access: yes, 2019
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone   +8 more
core   +2 more sources

Enantioselective Protonation of Radical Anion Intermediates in Photoallylation and Photoreduction Reactions of 3,3-Diaryl-1,1-dicyano-2-methylprop-1-ene with Allyltrimethylsilane

open access: yesMolecules, 2019
Photoreactions of acetonitrile solutions of 3,3-diaryl-1,1-dicyano-2-methylprop-1-enes (1a–c) with allyltrimethylsilane (2) in the presence of phenanthrene as a photoredox catalyst and acetic acid as a proton source formed photoallylation (3) and ...
Hajime Maeda   +3 more
doaj   +1 more source

Chirality in optical trapping and optical binding [PDF]

open access: yes, 2015
Optical trapping is a well-established technique that is increasingly used on biological substances and nanostructures. Chirality, the property of objects that differ from their mirror image, is also of significance in such fields, and a subject of much ...
Ahuja   +6 more
core   +2 more sources

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