Results 131 to 140 of about 511,953 (205)

Excess Insurance Company Limited

Placa en composición vertical. En la parte izquierda podemos ver el logo de la compañía, en la zona central el texto: "EXCESS INSURANCE COMPANY LIMITED", "representada por Excess servicios técnicos S.
Excess Insurance Company Limited
core  

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

On Serine Octamer Substitution Reactions

Rapid Communications in Mass Spectrometry, Volume 40, Issue 23, 15 December 2026.
ABSTRACT Rationale Monomeric amino acids substitute into the ionized serine octamer (Ser8), a magic number cluster that exhibits chiral behavior. Small biomolecules, such as amino acids (AA), substitute into the octamer enantioselectively, giving Ser7AAH+ and Ser6AA2H+ favoring clusters of all L‐ or all D‐chirality.
Brison A. Shira, Alana K. E. Thomas, R. Graham Cooks   +2 more
wiley   +1 more source

The asymmetric synthesis of (+)-sitophilure, the natural form of the aggregation pheromone of Sitophilus oryzae L. and Sitophilus zeamais M.

Journal of the Brazilian Chemical Society, 1999
The asymmetric synthesis of (+)-sitophilure, the aggregation pheromone of Sitophilus oryzae L. and Sitophilus zeamais M., was carried out in 12 steps, 18% overall yield and 82% enantiomeric excess from the enzymatic reduction of methyl 3-oxopentanoate ...
Pilli Ronaldo A., Riatto Valéria B.
doaj  

Magnetic circular dichroism in Archean atmosphere and asymmetric photolysis of biomolecules: enantiomeric excess of prebiotic sugar. [PDF]

J Biol Phys, 2020
Sharma A.
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Rapid Quantitative Determination of Enantiomeric Excess by Vibrational Circular Dichroism Using Noise Based Spectral Selection. [PDF]

Chirality
Jackson AM, Bows JR, Nash GR.
europepmc   +1 more source

Clinopodium nepeta Essential Oil and Its Major Constituents Pulegone and Menthone: Composition and Activity Against Verticillium dahliae, Phytophthora infestans, and Macrophomina phaseolina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Chemical fractionation of Clinopodium nepeta essential oil reveals pulegone and menthone as markedly more potent antifungal isolates than the whole oil, with activity varying among pathogens. Pulegone exhibits superior efficacy against Verticillium dahliae and Phytophthora infestans, whereas menthone shows enhanced activity against Macrophomina ...
Mohamed Taibi, Amine Elbouzidi, Mounir Haddou, Abdessamad Beraich, Abdellah Baraich, Reda Bellaouchi, Mohamed Addi, Khalid Chaabane, Bassem Jaouadi, Nadia Zarai, Bouchra El Guerrouj, Abdeslam Asehraou   +11 more
wiley   +1 more source

Determination of Enantiomeric Excess in Confined Aprotic Solvent. [PDF]

ACS Electrochem
Farrell EB, McNeill F, Duleba D, Martínez-Aviño A, Guiry PJ, Johnson RP.   +5 more
europepmc   +1 more source

Extracellularly Activatable Conjugates of RGD Peptidomimetics and Cryptophycin for αVβ3‐Targeted Cancer Therapy

Chemistry – A European Journal, Volume 32, Issue 37, 1 October 2026.
Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt, Henriette Hartung, Jonah Kammer, Norbert Sewald   +3 more
wiley   +1 more source