Results 141 to 150 of about 511,953 (205)

Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates

Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.
An alkyne‐tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the Kennedy pathway, allowing CuAAC‐based visualization of PE and affinity capture of PE‐conjugated LC3, ubiquitin, and GPI‐anchored proteins.
Yuan‐Ting Cho, Cindy Y. Jao, Zijun Xia, Brittany M. White‐Mathieu, Adrian Salic, Jeremy M. Baskin   +5 more
wiley   +2 more sources

Helix Regulation of Poly(phenylacetylene)s through the Interplay between Enantiomeric Excess and Temperature-Triggered Pendant Isomerization. [PDF]

Precis Chem
Wang D, Li W, Cheng J, Xu X, Chu X, Feng Z, Sheng N, Lin L, Zhang H, Chen X, Zou G.   +10 more
europepmc   +1 more source

High Enantiomeric Excess In-Loop Synthesis of d-[methyl-¹¹C]Methionine for Use as a Diagnostic Positron Emission Tomography Radiotracer in Bacterial Infection. [PDF]

ACS Infect Dis, 2020
Stewart MN, Parker MFL, Jivan S, Luu JM, Huynh TL, Schulte B, Seo Y, Blecha JE, Villanueva-Meyer JE, Flavell RR, VanBrocklin HF, Ohliger MA, Rosenberg O, Wilson DM.   +13 more
europepmc   +1 more source

Stereodynamics of Hemiacetal Formation in Pyridine‐3‐Carbaldehyde and Pyrimidine‐5‐Carbaldehyde Derivatives: Implications for the Soai Reaction

Chirality, Volume 38, Issue 10, October 2026.
Kinetic studies of the hemiacetal formation of pyridine‐3‐carbaldehyde and pyrimidine‐5‐carbaldehyde derivatives with alcohols by 1H NMR and dynamic HPLC show a high correlation between hemiacetal formation and autocatalytic reactivity in Soai's asymmetric autocatalysis with Gibbs activation energies between 85.9 and 95.5 kJ/mol.
Patrick Möhler, Alexander F. Siegle, Oliver Trapp   +2 more
wiley   +1 more source

Scalable ω‐Substituted α‐Olefins via Living Chain Transfer Telomerization: A Platform for Next Generation Polyolefins

Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.
A highly versatile and general strategy is presented for the scalable production of practical quantities of ω‐substituted α‐olefins using tris(ω‐substituted alkyl)aluminum telogens that are readily available through a “green” synthesis from commodity triisobutylaluminum and ethene as the taxogen. These new α‐olefins can be designed and used as monomers
Lauren G. Logue, Cole M. Burrows, Vince J. Wedekind, Hyunku C. Kim Jr., Lawrence R. Sita   +4 more
wiley   +2 more sources

EnzyKR: a chirality-aware deep learning model for predicting the outcomes of the hydrolase-catalyzed kinetic resolution. [PDF]

Chem Sci, 2023
Ran X, Jiang Y, Shao Q, Yang ZJ.
europepmc   +1 more source

Exploiting Biocatalysis for the Scalable Synthesis of Enantiopure γ‐Hydroxynitrile Building Blocks

European Journal of Organic Chemistry, Volume 29, Issue 37, 1 October 2026.
Screening a panel of (S)‐and (R)‐selective alcohol dehydrogenases identified several biocatalysts for stereoselectively reducing γ‐ketonitriles into γ‐hydroxynitriles. These processes were optimized, delivering the targets in yields up to 88% with e.e.’s up to 99%. Scalability of the methodology was achieved to produce gram quantities of product, which
Benjamin Baumert, Kathryn Yeow, Roi Boris Tchuemmogne Tchuente, Adam Cruise, Christopher Thomas, Thomas Bayer, Uwe T. Bornscheuer, Marcus Baumann   +7 more
wiley   +1 more source

Determination of the Molar Fraction and Enantiomeric Excess of Electrosprayed Amino Acid Anions Employing Photoelectron Circular Dichroism. [PDF]

Anal Chem
Both JH, Beliakouskaya A, Weitzel KM.
europepmc   +1 more source

Competing Charge Transport Pathways: A Spirobifluorene‐Based Molecular Loop

European Journal of Organic Chemistry, Volume 29, Issue 37, 1 October 2026.
A rigid molecular loop integrating a spirobifluorene (SBF) core with a cycloparaphenylene (CPP) moiety provides two distinct transport channels. Through‐space spiroconjugation and radial π‐conjugation along a CPP backbone coexist within a single molecule.
Brian Ogi, Riccardo Conte, Salome L. Heim, Herre S. J. van der Zant, Marcel Mayor   +4 more
wiley   +1 more source

Enantiomeric Excess Bupivacaine in a Lavender Oil NLC Tested in a Melanoma Model: Prolonged Release and Anticancer Effect. [PDF]

Mol Pharm
Geronimo G, Rodrigues da Silva GH, de Moura LD, de Carvalho FV, Mendonça TC, Olivo LB, Verlindo de Araújo B, Dalla Costa TC, Lavareze L, Mariano FV, de Paula E.   +10 more
europepmc   +1 more source