Results 151 to 160 of about 48,679 (293)

RETRACTED: Tomassoni et al. Brain Activity of Thioctic Acid Enantiomers: In Vitro and In Vivo Studies in an Animal Model of Cerebrovascular Injury. <i>Int. J. Mol. Sci.</i> 2013, <i>14</i>, 4580-4595. [PDF]

Int J Mol Sci
Tomassoni D, Amenta F, Amantini C, Farfariello V, Di Cesare Mannelli L, Nwankwo IE, Marini C, Tayebati SK.   +7 more
europepmc   +1 more source

The interplay between molecular architecture, pharmacology, and suspected adverse drug reactions associated with nonsteroidal androgen antagonists in the United Kingdom

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon, Albert A. Antolin, Alan M. Jones   +2 more
wiley   +1 more source

Dynamic breaking of mirror symmetry in spin-dependent electron transport through chiral media causes enantiomeric excesses. [PDF]

Sci Adv
Paltiel Y, Goldberg D, Yuran N, Yochelis S, Soh JH, Seibel C, Gauss J, Zilberg S, Ozturk SF, Fransson J, Krylov AI, Naaman R.   +11 more
europepmc   +1 more source

Exploration of structure–activity relationship of 2,4‐diaminopyrimidine derivatives as hematopoietic progenitor kinase 1 inhibitors

Bulletin of the Korean Chemical Society, EarlyView.
Targeting HPK1 is a promising strategy to restore T‐cell anti‐tumor immunity. We report the design and synthesis of novel 2,4‐diaminopyrimidine derivatives, focusing on systematic structure–activity relationship (SAR) analysis These findings identify key structural features for potent HPK1 inhibition, facilitating the discovery of next‐generation ...
Heechan Shin, Mi‐Ran Byun, Joon Seok Choi, Sujin Lee   +3 more
wiley   +1 more source

Synthesis, Properties, and Enantioseparation of Four-Ring Racemic Smectics. [PDF]

Materials (Basel)
Wojda E, Zając M, Perkowski P, Urbańska M.   +3 more
europepmc   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Beyond the Solid Solution: Ordered Enantiomerically Unbalanced Packing in Surface-Confined Tetrahelicene Monolayers. [PDF]

Chirality
Cebrat A, Martin K, Mutombo P, Parschau M, Avarvari N, Ernst KH.   +5 more
europepmc   +1 more source

Chromatographic fractionation of enantiomers of antithrombotic agents

, 2016
Suuri osa käytössä olevista lääkeaineista on kiraalisia yhdisteitä. Lääkevalmisteet sisältävät yhdisteen enantiomeerien ominaisuuksista riippuen joko yksittäistä enantiomeeria tai näiden seosta.
Ojanen, Jennina
core  

Separation Technique of Enantiomers

Analytical Sciences, 2020
openaire   +3 more sources

Decoupling Redox Potentials and Excited State Energies in Substituted Chromium(III) Chromophores

Chemistry – A European Journal, EarlyView.
Redox and excited state properties of organic and precious metal CT photocatalysts are strongly entangled. In contrast, redox potentials of polypyridine chromium(III) complexes, that feature purely metal‐centered SF states, are selectively tuned by incremental substituent effects of the CF3 group, while excited state energies and lifetimes remain ...
Steven Sittel, Dimitri Zorn, Alexandra König, Jonas Marcel Grenz, Christoph Förster, Robert Naumann, Katja Heinze   +6 more
wiley   +1 more source