Results 171 to 180 of about 56,768 (286)

Chiral Quasi‐BICs Stemming From a Γ‐point Degeneracy

Laser &Photonics Reviews, EarlyView.
Band degeneracies universally exist in 2D periodic systems. However, the studies on the intrinsic properties of those isolated points remain limited. By exploring 3D chiral perturbations, chiral quasi‐BICs are achieved through a Γ‐point degeneracy in resonant metasurfaces with C4 symmetry.
Bohan Zhang, Dongha Yang, Yuhao Wu, Mingqi Zheng, Wei Zhu, Lei Kang, Kang Du, Douglas H. Werner, Shengxiang Wang   +8 more
wiley   +1 more source

Chiral HPLC Separation of Phosphonothrixin and Phosphonate Derivatives and Electronic Circular Dichroism Characterization of the Isolated Enantiomers. [PDF]

Electrophoresis
Maalouf M, Knab M, Gessner L, Engelhardt M, Friedrich S, Gross H, Boeckler F, Hughes CC, Lämmerhofer M.   +8 more
europepmc   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Emergence of Chiral Defective Pores Through Chiral Linker Exchange in Nonchiral MOFs for Enantioselective Recognition. [PDF]

Angew Chem Int Ed Engl
Han Z, Wang KY, Huo J, Rushlow J, Liu Z, Yang Y, Liang RR, Shi W, Zhou HC.   +8 more
europepmc   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

NMR‐Based Structural Elucidation of a New Dihydroisocoumarin and Related Polyketides From a Mangrove‐Derived Fusarium sp.

Magnetic Resonance in Chemistry, EarlyView.
Integration of bioactivity screening and LC–MS/MS metabolomics enabled the discovery of a new antibacterial dihydroisocoumarin from Fusarium sp. IQ‐1921. NMR‐based structural elucidation identified five related metabolites, with the new compound 1 showing the broadest activity against multidrug‐resistant bacteria. ABSTRACT Antimicrobial resistance (AMR)
Evelyn García‐Oceguera, Carlos A. Fajardo‐Hernández, Ixchel A. Loa‐Ramírez, Jesús I. Morales‐Jiménez, José Rivera‐Chávez   +4 more
wiley   +1 more source

Circularly polarized luminescence as a contingency assay for 'mirror life' bio-hazards. [PDF]

R Soc Open Sci
MacKenzie LE, Black DJ, Pal R.
europepmc   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Co-assembly and self-sorting are not mutually exclusive in enantiomeric peptide systems. [PDF]

Chem Sci
Bianco S, Sonani RR, Marshall LJ, Loch AS, Doutch J, Egelman EH, Adams DJ.   +6 more
europepmc   +1 more source