Results 191 to 200 of about 48,679 (293)

Enantiospecific Optical Sensing of Terpenes by an Aggregated Atropisomeric Platinum(II) Complex. [PDF]

Angew Chem Int Ed Engl
Huber A, Prescimone A, Sparr C, Wenger OS.   +3 more
europepmc   +1 more source

Pharmacokinetics of ketamine enantiomers

British Journal of Anaesthesia, 1995
G, Geisslinger, W, Hering, H D, Kamp, K O, Vollmers   +3 more
openaire   +2 more sources

Synthesis and Structure of an S‐Shaped Double Expanded Helicene With Seven Fused Anthracene Units

Chemistry – A European Journal, EarlyView.
The anthracene‐fused aromatic compound was synthesized by four‐fold cycloisomerization of the corresponding alkyne precursor. X‐ray crystallographic analysis revealed that this compound had a double helical structure of Ci symmetry, in which the terminal and central anthracene units were triply stacked.
Shinji Toyota, Kaito Hohno, Takehiro Kihara, Yu Watanabe, Yuki Shigihara, Eiji Tsurumaki, Masahiro Yamashina   +6 more
wiley   +1 more source

Inducing configurational stability in inherently flexible expanded heterohelicenes and unlocking stimuli-responsive chiroptical switching. [PDF]

Chem Sci
Pal M, Karak P, Hati D, Giri M, George SJ, Choudhury J.   +5 more
europepmc   +1 more source

Anisotropy Factor Spectra for Weakly Allowed Electronic Transitions in Chiral Ketones

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
Anisotropy factor spectra for the weak n→π*‐type A‐band of chiral ketones cannot be described within the Franck–Condon approximation. Thus, we present such spectra computed by accounting for Herzberg–Teller corrections and compare them to experiments for fenchone, camphor and 3MCP to describe chiroptical properties of these molecules in the mid to near
Leon A. Kerber, Oliver Kreuz, Tom Ring, Hendrike Braun, Robert Berger, Daniel M. Reich   +5 more
wiley   +1 more source

Enhanced chiral discrimination in mass spectrometry with orbital angular momentum beams. [PDF]

Sci Adv
Venugopal H, Aravind P, Sajeevan A, Sen S, Sinha A, Giri S, Dixit G, Gopal R, Sharma V.   +8 more
europepmc   +1 more source

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Chiral separation of aromatic amino acids by capillary electrophoresis using sulphated β-cyclodextrin as a single chiral selector: an experimental and computational study. [PDF]

RSC Adv
Elbashir AA, Bano R, Fiser B, Schmitz OJ.   +3 more
europepmc   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Highly luminescent carbazole-functionalized tris(tribromophenyl)methyl radicals with stable circularly polarized photoluminescence. [PDF]

Nat Commun
Schöneburg L, Gross M, Thielert P, Zolg J, Arnold ME, Schuster PA, Putz B, Richert S, Kuehne AJC.   +8 more
europepmc   +1 more source