Bakuchiol: From structural mimicry to systems‐level skin biology
International Journal of Cosmetic Science, EarlyView.Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley +1 more source
Aerogel Pore-Confined High-Loading MOF-199 for Micro-Solid-Phase Extraction of Methorphan Enantiomer in Biological Samples. [PDF]
J Sep SciHuang S +7 more
europepmc +1 more source
Narcolepsy and rapid eye movement sleep
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini +4 more
wiley +1 more source
Derivatization-Assisted Lipase-Mediated Separation of Optically Pure α-Cyclopentylmandelic Acid Through Enhanced Substrate Recognition. [PDF]
MoleculesZhao Y, Li Z, Long X, Lu Q.
europepmc +1 more source
Pursuing patents for their own sake: How the investment discourse shapes patent quality and quantity
The Journal of World Intellectual Property, EarlyView.Abstract Patent systems worldwide face criticisms over declining patent quality and increasing patent quantity. While most research focuses on strengthening examination rigour, this article turns attention to relatively underexplored patenting incentives.
Li Liu
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Application of Analytical Techniques to Chiral Amino Acid Profiling in Clinical Samples: Bridging Chemistry and Disease Research. [PDF]
ChiralityChawathe A, Sanju, Sahane P, Sharma N.
europepmc +1 more source
Probing the molecular determinants of emission enhancement in RNA aptamer–metal complex systems
Photochemistry and Photobiology, EarlyView.Light up aptamer: fluorophore pairs are widely used in sensing and imaging, with coordination complex fluorophores providing specific benefits due to their long‐lived emission. Here, we examined key structural and electronic features of these metal complexes to identify the requirements for productive engagement with an RNA aptamer.
Sarah M. Kriger +3 more
wiley +1 more source
Distribution of citalopram enantiomers following medication with racemic citalopram - a naturalistic therapeutic drug monitoring study. [PDF]
Eur J Clin PharmacolEspnes KA +3 more
europepmc +1 more source
Molecular Targets and Biological Activities of Carvone: An Evidence-Graded Review. [PDF]
MoleculesDvořák Z, Hrubý J.
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