Results 201 to 210 of about 48,679 (293)

Pd‐Catalyzed Cyclotrimerization and Cycloaddition of 5,6‐Didehydrobenzo[8]annulenes (BenzoCOTynes): Formation of Nonplanar Tri[8]annulenes and Diels–Alder Cycloadducts

European Journal of Organic Chemistry, EarlyView.
A Pd(0)‐catalyzed cyclotrimerization of benzoCOTynes to form tri(benzo[8]annulenes) was developed. Three distinct isomers were isolated and structurally characterized by single‐crystal X‐ray diffraction. Ligand modulation proved crucial for enhancing regioselectivity: P(4‐OMePh), and (S)‐tBu‐Phox promoted the formation of the symmetric isomers.
Jesús Bello‐García, Jesús A. Varela, Carlos Saá   +2 more
wiley   +1 more source

Dibenzosuberene‐Winged Polycyclic Aromatic Hydrocarbons

European Journal of Organic Chemistry, EarlyView.
The twisted acene 8, which features two dibenzosuberene “wings”, was prepared by the addition of a crowded aryne to a similarly “winged” cyclopentadienone. Compound 8 is chiral, and it has a high barrier to thermal racemization (ΔG‡rac = 36 kcal/mol), but it undergoes fast photochemical racemization even in ambient light.
Mingshu Xie, Xiaodong Zhang, Michael W. Johnson, Robert A. Pascal Jr   +3 more
wiley   +1 more source

Stereoselectivity and functional plasticity of a common ligand-binding pocket in TRPM3. [PDF]

Nat Commun
Bazeli B, Shkumatov AV, Schenck S, Vanherck JC, Janssens A, Spieser SAH, Marchand D, Roelens R, Chaltin P, Marchand A, Vriens J, Voets T, Brunner JD.   +12 more
europepmc   +1 more source

Enantiospecific Acid‐Catalysed Hydroperoxidation of Scalemic Tertiary Benzylic Alcohols Facilitating a Concise Asymmetric Synthesis of Yingzhaosu C

European Journal of Organic Chemistry, EarlyView.
Asymmetric synthesis of antimalarial yingzhaosu C was achieved in 4–5 steps by asymmetric Grignard synthesis of (R)‐gossonorol followed by novel enantiospecific hydroperoxidation. We report a concise asymmetric synthesis of antimalarial yingzhaosu C in 59% ee.
Saranna E. Kavanagh, Claudio Monasterolo, Declan G. Gilheany   +2 more
wiley   +1 more source

The Binding of 3-O-Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation. [PDF]

Chembiochem
Troisi R, Rullo R, Napolitano V, Popowicz GM, De Vendittis E, Sica F.   +5 more
europepmc   +1 more source

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

ELECTROPHORESIS, EarlyView.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam   +3 more
wiley   +1 more source

Comparison of Pleated and Rippled β-Sheet Assembly of Sequence Isomers of an Amphipathic Self-Assembling Peptide. [PDF]

Biochemistry
Jones CW, Chen J, Panda R, Jalali S, Cardani LP, Guo Y, Arnold IM, Dias CL, Nilsson BL.   +8 more
europepmc   +1 more source

Probing Chiral Recognition on Amylose Tris(3,5‐Dimethylphenylcarbamate) Using Cinnamyl 2‐Aminoanilides: The Subtle Impact of Aliphatic Substituents

ELECTROPHORESIS, EarlyView.
This study investigates how subtle aliphatic substituent differences in racemic cinnamyl 2‐aminoanilides affect chiral recognition on amylose tris(3,5‐dimethylphenylcarbamate). Pronounced enantioselectivity changes arose from minimal structural variations. Mobile phase effects were examined, with 2‐propanol improving resolution.
Selen Gözde Kaya, Alessia Raucci, Clemens Zwergel, Antonello Mai, Sergio Valente, Roberto Cirilli   +5 more
wiley   +1 more source

Advances in Enantioselective Synthesis and Chiral Resolution of Insecticides. [PDF]

Molecules
López-Rosas CA, Delgado-Alvarado E, Barrera-Méndez F, Bonilla-Landa I, Olivares-Romero JL.   +4 more
europepmc   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source