Results 221 to 230 of about 48,679 (293)

Integrated pretreatment and fermentation strategies for L‐lactic acid production from brewers' spent grain using native Streptococcus infantarius and Bacillus coagulans

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Brewers' spent grain (BSG) is an abundant lignocellulosic byproduct of the brewing industry with strong potential as a renewable substrate for biotechnological production of lactic acid (LA). This study evaluated integrated pretreatment, enzymatic hydrolysis, and fermentation strategies to enable efficient production of optically ...
Mónica Olvera, Carmen G. Hernández‐Valencia, Carmina Montiel, Agata Olszewska‐Widdrat, Joachim Venus, Miquel Gimeno   +5 more
wiley   +1 more source

Discovery and Optimization of Potent and Subtype-Selective Urea-Derived Na_V1.8 Inhibitors. [PDF]

ACS Med Chem Lett
Dialer C, Krüger S, Wagener M, Mülbaier M, Peil S, Marigo M, Hagendorf S, Cao L, Molina CR, Morgan P, Young C, Ribeiro LR, Slynko I, Ritter S, Guberman M, Hass M, Klosky S, la Tendresse U, Gussmann C, Kühnert S, Peters S, Reichardt-Ockenfeld S, Depmeier H, Jakob F.   +23 more
europepmc   +1 more source

Photooxidation of 18‐Carbon Polyunsaturated Fatty Acids to Prepare Mono‐Hydroxylated Octadecanoids

Lipids, EarlyView.
We developed a fast and simple one‐step synthetic strategy to produce mono‐hydroxylated metabolites based on the photosensitized oxidation of 18‐carbon polyunsaturated fatty acids (PUFAs). This approach could likely be extended to other PUFAs, suggesting that photosensitized oxidation could be employed to rapidly prepare hydroperoxides from multiple ...
Johanna Revol‐Cavalier, Mats Hamberg, Craig E. Wheelock   +2 more
wiley   +1 more source

Rapid enantioselective fluorescence recognition and chiral separation of free amino acids. [PDF]

Nat Commun
Li Y, Yu K, Xu Z, Zeng J, Wei J, Jiang H, Zhu Y, Gu S, Ma X.   +8 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

π-Aggregation-free, fused perylene pentamers: synthesis, narrowband far-red to near-infrared emission, and chiroptical properties. [PDF]

Chem Sci
Zhou Q, Bao LT, Liu R, Sun Z, Ye Z, Jiao L, Fan W, Zou Y, Yang HB, Wu J.   +9 more
europepmc   +1 more source

Emerging Agents for Boron Neutron Capture Therapy: Biomolecular Carriers Paving the Way for Precision Radiotherapy

Precision Radiation Oncology, EarlyView.
Boron neutron capture therapy (BNCT) requires key non‐negotiable technical criteria: megadose administration, precise tumor‐specific targeting, favorable biocompatibility, and sustained tumor retention. Overcoming these interconnected challenges fundamentally depends on biomolecular carriers, which are critical for translating the therapeutic potential
Chang Chen, Maosong Yang, Jiheng Wang, Ling Zhang, Shaobo Huang, Xiao Xu, Yang Liu   +6 more
wiley   +1 more source

Multi-Center Catalytic Oxidation of the Sotalol Drug Adsorbed on Gold Nanoparticles. [PDF]

Molecules
Kolobova EA, Makarova KN, Solovyeva EV.
europepmc   +1 more source

17‐epi‐Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae

Pest Management Science, EarlyView.
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Kethleen Duarte Crespo Soares, Thalya Soares Ribeiro Nogueira, Maria Aparecida Aride Bertonceli, Renata Rodrigues da Silva Robaina, Leticia Oliveira da Rocha, Francisco José Alves Lemos, Kátia Valevski Sales Fernandes, Raimundo Braz‐Filho, Ivo José Curcino Vieira   +8 more
wiley   +1 more source

Fluoxetine inhibits severe acute respiratory syndrome coronavirus 2 replication in vitro.

Indian J Pharmacol
Vityala Y, Tagaev T, Mainazarova E, Aidarov Z, Karthik M.   +4 more
europepmc   +1 more source