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Enantiomer fractions instead of enantiomer ratios

Chemosphere, 2000
The use of enantiomer ratios (ERs) to indicate the relative amounts of a pair of enantiomers in a sample has some disadvantages. Enantiomer fractions (EFs) are proposed as an alternative expression to eliminate the difficulties.
de Geus, H.J.   +3 more
openaire   +4 more sources

Enantiomer–enantiomer interaction of ifosfamide in the rat

Xenobiotica, 2006
The objective of this study was to study the enantiomer-enantiomer interaction of ifosfamide (IFA) in a rat model. Following intravenous administration of individual IFA enantiomers or pseudo-racemates to male Sprague-Dawley rats, two enantiomers and their metabolites, 4-hydroxyIF (HOIF), N2-dechloroethylIF (N2D), N3-dechloroethylIF (N3D), and ...
H, Lu, J J, Wang, K K, Chan
openaire   +2 more sources

The Enantiomer of Cholesterol

The Journal of Membrane Biology, 2004
Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol)--which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol--is a unique tool that can be used to better
E J, Westover, D F, Covey
openaire   +2 more sources

Processes To Separate Enantiomers [PDF]

open access: yesAngewandte Chemie - International Edition, 2014
AbstractThe provision of pure enantiomers is of increasing importance not only for the pharmaceutical industry but also for agrochemistry and biotechnology. In general, there are two rival approaches to provide pure enantiomers. The “chiral” approach is based on developing an asymmetric synthesis of just one of the enantiomers, while the “racemic ...
Heike Lorenz
exaly   +4 more sources

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