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Enantiomer specific pharmacokinetics
Pharmacology & Therapeutics, 1990To indicate the extent of differences in the pharmacokinetics of enantiomers with respect to absorption and disposition phenomena. To emphasise the potential benefits of studying enantiospecific pharmacokinetics, that is, kinetics based on the measurement of the time-course of separate isomers rather than of the total, racemic drug ...
G T, Tucker, M S, Lennard
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Enantiomers in arthritic disorders
Pharmacology & Therapeutics, 1990Drugs which have a center of asymmetry are often administered as an equal mixture of the two possible enantiomeric forms i.e. a racemate. However, there are frequently large pharmacodynamic and pharmacokinetic differences between enantiomers. Consequently, it is possible that while one enantiomer mediates the antiinflammatory or antirheumatic action ...
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Kinetics of misonidazole enantiomers
Clinical Pharmacology and Therapeutics, 1984The kinetics of misonidazole enantiomers were followed in nine healthy subjects after a single oral dose of racemic misonidazole (1.0 gm/m2). Mean clearance of (+)-misonidazole was 14% greater than that for (-)-misonidazole and mean volume of distribution was slightly greater (3%) for the (+)-enantiomer.
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Characterization of key aroma compounds and enantiomer distribution in Longjing tea
Food Chemistry, 2021Yin Zhu, Zuobing Xiao
exaly
Chiral graphene materials for enantiomer separation
Chemical Engineering Journal, 2023Zunli Mo
exaly
Enantiomers of Warfarin and Phenobarbital
New England Journal of Medicine, 1976M, Orme, A, Breckenridge
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Chiral membranes for enantiomer separation: A comprehensive review
Separation and Purification Technology, 2022Zunli Mo
exaly