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An Update: Enzymatic Synthesis for Industrial Applications

open access: yesAngewandte Chemie International Edition, Accepted Article.
Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer   +4 more
wiley   +1 more source

An enantioselective synthesis of isoquinuclidines from 3-substituted chiral pyridinium salts [PDF]

open access: green, 2001
Daniela Cristina dos Santos   +3 more
openalex   +1 more source

De Novo Enantioselective Synthesis of Hexafluorinated d-Glucose. [PDF]

open access: yesJ Org Chem
Depienne S   +4 more
europepmc   +1 more source

Highly Enantioselective Organocatalysis with Bidentate Halogen Bond Donors

open access: yesAngewandte Chemie International Edition, Accepted Article.
As the employment of ”non‐classical” non‐covalent interactions like halogen bonding (XB) in asymmetric catalysis is still at a very early stage, there are significant challenges to overcome. In some reported cases, the relevance of halogen bonding to the catalytic action is unclear, while in others, catalyst activity is limited.
Julian Wolf   +6 more
wiley   +1 more source

Microwave-Assisted Enantioselective Synthesis of (2<i>R</i>,5<i>S</i>)-Theaspirane: A Green Chemistry Approach. [PDF]

open access: yesMolecules
Takada SCS   +5 more
europepmc   +1 more source

Total Synthesis of Isodaphlongamine H by Iridium‐Catalyzed Reductive [3+2] Cycloaddition of N‐Hydroxylactam

open access: yesAngewandte Chemie International Edition, Accepted Article.
The total synthesis of isodaphlongamine H based on a lactam strategy, which enables quick access to complex cyclic amines, is described. The strategy begins with alkylation of a chiral lactam and subsequent N‐oxidation via an imino ether to afford the N‐hydroxylactam.
Sora Iwamoto   +15 more
wiley   +1 more source

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