Results 161 to 170 of about 2,821 (224)

Elucidating Chiral Resolution of Aromatic Amino Acids Using Glycopeptide Selectors: A Combined Molecular Docking and Chromatographic Study. [PDF]

open access: yesInt J Mol Sci
Gherdaoui D   +11 more
europepmc   +1 more source

Enantioseparation of the antidepressant reboxetine

open access: yesJournal of Pharmaceutical and Biomedical Analysis, 2008
The enantioseparation of reboxetine by HPLC was investigated using chiral stationary phases (CSPs) containing cellulose Tris(3,5-dimethylphenyl)carbamate on silica gel (Chiralcel OD column) as the chiral selector. Reversed phase HPLC was the technique of choice for the analytical enantioseparation of reboxetine, while the chiral semipreparative ...
CANNAZZA, Giuseppe   +7 more
openaire   +5 more sources

Enantioseparation and racemization of 3‐fluorooxindoles

Chirality, 2023
AbstractFluorinated oxindoles are frequently used building blocks in asymmetric synthesis and represent an important scaffold found in a variety of biologically relevant compounds. While it is understood that incorporation of fluorine atoms into organic molecules can improve their pharmacological properties, the impact on the configurational stability ...
Andi Yuan   +4 more
openaire   +2 more sources

Enantioseparations by capillary electrochromatography

ELECTROPHORESIS, 2001
The review summarizes recent developments in enantioseparations by capillary electrochromatography (CEC). Selected fundamental aspects of CEC are discussed in order to stress those features which may allow the success of this technique in the competitive field of enantioseparations. In addition, the comparative characteristics of the different modes of
Salvatore Fanali   +3 more
openaire   +5 more sources

Enantioseparation of tiropramide by HPLC

Chirality, 2004
Tiropramide is an antispasmodic drug that has a chiral center. Resolution of tiropramide enantiomers on various kinds of chiral stationary phases was performed by HPLC. A good resolution on a leucine-derived chiral stationary phase was found. An improved chromatographic condition to resolve racemic tiropramide on the CSP was examined by changing the ...
Jae Jeong, Ryoo   +4 more
openaire   +2 more sources

Progress in microchip enantioseparations

ELECTROPHORESIS, 2009
AbstractAdvances in microfluidic chips for chiral separations from 2003 to early 2009 are discussed. Microchip‐based separation techniques promise higher speed, throughput, portability, less sample and reagent consumption, better environmental compatibility, reduced cost and the prospect of system integration.
Nagl, Stefan   +3 more
openaire   +4 more sources

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