Results 161 to 170 of about 5,412 (216)
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Homochiral metal–organic frameworks for enantioseparation
Chemical Society Reviews, 2021Contextualising rational structural design, according to the enantioselective mechanisms of homochiral metal–organic frameworks, we discuss enantioselective separations primed to deliver purification performances and analytical utilities thereof.
Soumya Mukherjee +2 more
exaly +3 more sources
Enantioseparations by capillary electrochromatography
ELECTROPHORESIS, 2001The review summarizes recent developments in enantioseparations by capillary electrochromatography (CEC). Selected fundamental aspects of CEC are discussed in order to stress those features which may allow the success of this technique in the competitive field of enantioseparations. In addition, the comparative characteristics of the different modes of
Salvatore Fanali +3 more
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Progress in microchip enantioseparations
ELECTROPHORESIS, 2009AbstractAdvances in microfluidic chips for chiral separations from 2003 to early 2009 are discussed. Microchip‐based separation techniques promise higher speed, throughput, portability, less sample and reagent consumption, better environmental compatibility, reduced cost and the prospect of system integration.
Nagl, Stefan +3 more
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Recent advances in electrodriven enantioseparations
Journal of Separation Science, 2012Capillary electromigration techniques have developed into significant analytical separation tools especially for enantioseparations. While CE can be considered a mature technique as documented by its wide applications, CEC is still in a developmental state despite many research efforts.
Pavel, Jáč, Gerhard K E, Scriba
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Enantioseparation and racemization of 3‐fluorooxindoles
Chirality, 2023AbstractFluorinated oxindoles are frequently used building blocks in asymmetric synthesis and represent an important scaffold found in a variety of biologically relevant compounds. While it is understood that incorporation of fluorine atoms into organic molecules can improve their pharmacological properties, the impact on the configurational stability ...
Andi Yuan +4 more
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Enantioseparation of tiropramide by HPLC
Chirality, 2004Tiropramide is an antispasmodic drug that has a chiral center. Resolution of tiropramide enantiomers on various kinds of chiral stationary phases was performed by HPLC. A good resolution on a leucine-derived chiral stationary phase was found. An improved chromatographic condition to resolve racemic tiropramide on the CSP was examined by changing the ...
Jae Jeong, Ryoo +4 more
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Enantioseparation of nonproteinogenic amino acids
Analytical and Bioanalytical Chemistry, 2009The enantioseparation of structurally related N-protected beta-/gamma-amino acids, beta-/gamma-amino amides, and beta-/gamma-amino nitriles by using six different commercially available chiral stationary phases (CSPs) is reported. The synthetic key step to introduce stereochemical asymmetry into all compounds is an enzymatic kinetic resolution of the ...
Margit, Winkler, Norbert, Klempier
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Enantioseparation of the antidepressant reboxetine
Journal of Pharmaceutical and Biomedical Analysis, 2008The enantioseparation of reboxetine by HPLC was investigated using chiral stationary phases (CSPs) containing cellulose Tris(3,5-dimethylphenyl)carbamate on silica gel (Chiralcel OD column) as the chiral selector. Reversed phase HPLC was the technique of choice for the analytical enantioseparation of reboxetine, while the chiral semipreparative ...
CANNAZZA, Giuseppe +7 more
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Enantioseparations by Thin-Layer Chromatography
2012An up-to-date overview of thin-layer chromatography (TLC) techniques for chiral separations of various significant and/or recent examples of enantioresolutions is reported. Furthermore, examples for chiral separations obtained on achiral commercially available C18 TLC plates are described in detail.
DEL BUBBA, MASSIMO +3 more
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