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Pharmacy‐Based Immunization Delivery: A Comprehensive History and Current Challenges
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.ABSTRACT Pharmacists and their teams have a long history of involvement with vaccines. This paper describes the contributions of pharmacy‐based immunization delivery in the United States from the 1800's to date. Early activities centered around storage and distribution of antitoxins and vaccines. From the 1950s through the early 1990s, pharmacists were
Jean‐Venable R. Goode +4 more
wiley +1 more source
The Involvement of Microglial Cells in Japanese Encephalitis Infections
Clinical and Developmental Immunology, 2012 Despite the availability of effective vaccines, Japanese encephalitis virus (JEV) infections remain a leading cause of encephalitis in many Asian countries.
Thananya Thongtan +2 more
doaj +1 more source
Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA
Journal of Medical Virology, Volume 98, Issue 6, June 2026.ABSTRACT Reverse genetics (RG) systems have transformed RNA virus research by enabling the recovery of recombinant viruses entirely from cloned cDNA. These platforms allow precise, hypothesis‐driven manipulation of viral genomes and support systematic phenotypic analyses in vitro and in vivo.
Young‐Min Lee
wiley +1 more source
, 1997 Theiler's murine encephalomyelitis virus was stereotaxically inoculated unilaterally into the substantia nigra of the mouse brain. Virus specifically infected tyrosine hydroxylase-positive neurons and spread rostrocaudally throughout this subpopulation ...
Brennan, P, Oliver, K R, Fazakerley, J K
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Japanese encephalitis in children
, 2016 Japanese encephalitis is a zoonotic disease causedby Japanese encephalitis virus, attacking domesticanimals, mainly pigs and birds. It is transmittedto humans by mosquito bites, namely Culextritaeniorhyncus.
W Cicilia +2 more
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Regulation of inflammation in Japanese encephalitis [PDF]
, 2017 Uncontrolled inflammatory response of the central nervous system is a hallmark of severe Japanese encephalitis (JE). Although inflammation is necessary to mount an efficient immune response against virus infections, exacerbated inflammatory response ...
Lannes, Nils +5 more
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Flaviviruses—Induced Neurological Sequelae
PathogensFlaviviruses, a group of single-stranded RNA viruses spread by mosquitoes or ticks, include several significant neurotropic viruses, such as West Nile virus (WNV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Zika virus ...
Samantha Gabrielle Cody +4 more
doaj +1 more source
Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines
Vox Sanguinis, EarlyView.
Pierre Tiberghien +4 more
wiley +1 more source
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1212-1224, June 2026.ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Inactivated Japanese Encephalitis Virus Vaccine; Recommendations of the Advisory Committee on Immunization Practices (ACIP) [PDF]
"Japanese encephalitis (JE) vaccine was available in the United States from 1983 through 1987 on an investigational basis, through travel clinics in collaboration with CDC (1).
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