Results 61 to 70 of about 126,056 (280)

Improved UNet‐based magnetic resonance imaging segmentation of demyelinating diseases with small lesion regions

open access: yesCognitive Computation and Systems, EarlyView.
Abstract Accurate magnetic resonance imaging (MRI) segmentation plays a critical role in the diagnosis and treatment of demyelinating diseases. But the existing automatic segmentation methods are not suitable for the segmentation of demyelinating lesions with small lesion size, highly diffuse edges and complex boundary shapes.
Minhui Liu   +4 more
wiley   +1 more source

Initiating Care of a Patient With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

open access: yesFrontiers in Pediatrics, 2019
This paper introduces the primary care physician to the unique and challenging aspects of initially diagnosing and managing a complex condition for which there are a plethora of symptoms, few physical findings, no known cause, and no specific treatments.
Charles W. Lapp
doaj   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Successful Treatment of Human Herpesvirus 6 Encephalomyelitis in Immunocompetent Patient

open access: yesEmerging Infectious Diseases, 2004
We report the case of human herpesvirus 6 (HHV-6) encephalomyelitis in an immunocompetent patient, which was confirmed by viral amplification from cerebrospinal fluid. Cidofovir was used followed by ganciclovir because of an adverse effect to probenecid.
Eric Denes   +5 more
doaj   +1 more source

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x‐ray phase‐contrast tomography

open access: yesBrain Pathology, EarlyView.
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz   +9 more
wiley   +1 more source

An unusual case of suspected lyme neuroborreliosis in a patient presenting with ear pain

open access: yesJournal of Global Infectious Diseases, 2019
We report a case of suspected Lyme neuroborreliosis (LNB) where the patient's sole symptom was chronic, intermittent episodes of unilateral ear pain.
Michael Anthony Ramada   +2 more
doaj   +1 more source

Comparative Cytokine and Histology Studies on HPV and Other Viral Vaccinations: No Pathogenicity of HPV Vaccine Adjuvants

open access: yesCancer Science, EarlyView.
Anti‐HPV vaccine activists claimed that aluminum (Al) adjuvants in HPV vaccines could cause immune abnormalities, leading to neurological diseases. We evaluated the cytokine and histology profiles following administrations of HPV vaccines and other viral vaccines containing adjuvants.
Reona Shiro   +9 more
wiley   +1 more source

Reply to “Neurophysiological Testing to Diagnose Stiff‐Person Spectrum Disorder”

open access: yes
Movement Disorders Clinical Practice, EarlyView.
João Moura   +5 more
wiley   +1 more source

Effect of time to initiation and dose of methylprednisolone on outcome in multiple sclerosis‐related optic neuritis

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Abstract Objectives It is known that the benefit of intravenous methylprednisolone (IVMP) in multiple sclerosis‐related optic neuritis (MS‐ON) is limited to an accelerated recovery. We aimed to evaluate the impact of time from symptoms onset to IVMP initiation and of IVMP dose on visual recovery among people with MS‐ON.
Hadar Gilad   +3 more
wiley   +1 more source

Features of Acute Neuroinfections in Clinical Hospital of Pediatric Infectious of Kyiv

open access: yesAktualʹnaâ Infektologiâ, 2015
We have analyzed the structure, course and clinical picture of 65 cases of acute neuroinfections in children, who were treated in the clinical hospital of pediatric infections of Kyiv in 2014.
V.V. Yevtushenko   +5 more
doaj   +1 more source

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